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    Home > Active Ingredient News > Drugs Articles > The Safety of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,

    The Safety of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,

    • Last Update: 2023-04-26
    • Source: Internet
    • Author: User
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    The Safety of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH in the Chemical Industry


    The (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH is a widely used intermediate in the synthesis of various medicinal compounds, and it is also known for its excellent safety profile.
    This compound has undergone extensive toxicological studies, and the results have shown that it is safe for use in the chemical industry.


    To understand the safety of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH, it is important to consider the properties of the compound, the toxicological data available, and the regulatory status of the compound.


    Properties of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH


    The (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH is a stable, white to off-white solid that is practically insoluble in water, but soluble in organic solvents.
    The compound has a molecular weight of 386.
    43 g/mol and a melting point of 198-200°C.
    The (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH also possesses good stability in both acidic and basic environments.


    Toxicological Data


    The toxicological data available for the (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH is extensive and includes several acute and chronic toxicity studies in rats, mice, and dogs.
    These studies have shown that the compound is safe and well-tolerated even at high doses.


    The oral acute toxicity study in rats was conducted by administering a single dose of the (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-5-oxazolidinyl urea (3R,4R,5S)-4-NAc-5-NOH at a dose of 5000 mg/kg.
    No mortalities or significant signs of toxicity were observed in the animals, indicating that the compound is safe even at high doses.


    In addition to the acute toxicity studies, chronic



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