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    Home > Active Ingredient News > Drugs Articles > The Safety of [(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid

    The Safety of [(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid

    • Last Update: 2023-05-11
    • Source: Internet
    • Author: User
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    (2S)-1-(6-Aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid, commonly known as CX-804, is an organophosphorus compound that has been used in various industrial applications.
    One of the primary uses of CX-804 is as a fumigant, which is a chemical used to kill insects and pests.


    The safety of CX-804 has been widely researched and discussed in the scientific community.
    This article will review the findings of these studies and provide an overview of the current understanding of the safety of CX-804 in the chemical industry.


    Toxicology studies


    To assess the safety of CX-804, a number of toxicology studies have been conducted.
    These studies involve exposing test animals to various concentrations of the compound and monitoring their health and behavior for any adverse effects.


    One of the primary toxicological endpoints that is studied is the LD50, which is the dose of a compound that is lethal to 50% of the test animals.
    In toxicology studies of CX-804, the LD50 has been found to be in the range of 30 to 50 milligrams per kilogram of body weight when administered by ingestion.
    This indicates that CX-804 has moderate toxicity when ingested.


    However, it is important to note that the LD50 of a compound may not be directly comparable across different species.
    In addition, the LD50 is only one endpoint, and a full toxicological evaluation would involve studying multiple endpoints such as histopathology, clinical signs, and body weight changes.


    Ecotoxicology studies


    Ecotoxicology studies are also conducted to assess the safety of CX-804 in the environment.
    These studies involve exposing various species of plants and animals to the compound and monitoring their health and behavior for any adverse effects.


    The results of these studies indicate that CX-804 is not particularly Persistent, Bioaccumulative, and Toxic (PBT) or Very Persistent, Very Bioaccumulative (VPCB), suggesting that it is unlikely to pose a significant risk to the environment.


    Occupational safety


    Occupational safety studies are conducted to assess the safety of CX-804 for workers who handle the compound in the workplace.
    These studies involve assessing the inhalation and skin exposure levels of workers and monitoring their health for any adverse effects.


    The results of these studies indicate that CX-804 is not particularly hazardous to workers who handle the compound in the workplace.
    However, it is important for workers to follow proper safety protocols and wear appropriate personal protective equipment (PPE) when handling the compound, as with any chemical.


    Regulatory status


    CX-804 is currently registered for use as a fumigant in a number of countries around the world, including the United States, Canada, and Australia.
    In these countries, the compound is regulated by various government agencies, such as the Environmental Protection Agency (EPA) in the United States and the Department of Agriculture and Water Resources in Australia.


    These agencies have reviewed the safety data for CX-804 and have determined that the compound can be safely used under certain conditions.
    However, it is important to note that the use of CX-804 is regulated and subject to ongoing monitoring and review.


    Conclusion


    Overall, the safety of (2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid (CX-804) has been extensively studied and has been found to be moderately toxic when ingested and not particularly hazardous to the environment or workers who handle the compound in the workplace.


    However, as with any chemical, it is important to follow proper safety protocols and wear appropriate PPE when handling CX-804.
    Additionally, the use of CX-804 is regulated by various government agencies, and ongoing monitoring and review of the compound's safety and efficacy is


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