The researchers determined the mechanism of tissue consumption for pancreatic cancer

, June 21st,
, suggests that changes in the exocrine function of the pancreas may be the cause of adipose tissue and skeletal muscle consumption in pancreatic cancer patients.
changes in cell metabolism are symptoms of various cancers. Epipenic tissue consumption is particularly associated with pancreatic cancer, a metabolic syndrome that reduces quality of life and is also thought to reduce survival rates in cancer patients. There are many causes of organizational consumption, but it has been difficult to determine the exact underlying mechanism.
Matthew Vander Heiden of the Massachusetts Institute of Technology, Brian Wolpin of the Dana Faber Cancer Institute in Massachusetts and colleagues used mouse pancreatic cancer models to find that adipose tissue and skeletal muscle consumption occur early in the disease's development, and that the outer tissue consumes the growth of pancreatic tumors, not other areas. The researchers said that decreased exocrine function of the pancreas promotes the loss of adipose tissue, and supplementation with pancreatic enzymes can reduce the consumption of surrounding tissue, but does not improve survival in mice.
65 percent of the 782 pancreatic cancer patients who were diagnosed with skeletal muscle depletion. However, adipose tissue and skeletal muscle consumption were not associated with reduced survival rates in patients. Therefore, the early on-stage exostation of pancreatic cancer may be an early warning sign of the disease, but may not be associated with a shorter survival period. (Source: Tang Erdu, China Science Daily)