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    Home > Active Ingredient News > Immunology News > The research group of Tang Dingzhong from Fujian Agriculture and Forestry University revealed the mechanism of rice 14-3-3 regulating the immune response mediated by GRAS protein OsSCL7

    The research group of Tang Dingzhong from Fujian Agriculture and Forestry University revealed the mechanism of rice 14-3-3 regulating the immune response mediated by GRAS protein OsSCL7

    • Last Update: 2022-05-02
    • Source: Internet
    • Author: User
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    Source: Plants and the Environment PCE Plants trigger a series of immune responses when they sense pathogenic infection.
    Transcriptional regulator-mediated transcriptional reorganization plays a key role in this process.
    Studies have shown that many types of transcription factors are involved in plant and Pathogen interactions
    .

    GRAS protein is a kind of protein unique to plants.
    It is mostly involved in the process of plant growth and development and stress in the form of transcriptional regulators.
    Studies have found that GRAS protein also plays an important role in plant immune response, but its function in plant immune process.
    and the regulatory mechanism remains unclear
    .

    Recently, Tang Dingzhong's research group from the Plant Immunity Research Center of Fujian Agriculture and Forestry University published a research paper entitled "The 14-3-3 Protein GF14c positively regulates immunity by modulating the protein homoeostasis of the GRAS protein OsSCL7 in rice" in Plant, Cell & Environment , expounded the important functions of GRAS protein OsSCL7 and 14-3-3 protein GF14c in plant immunity, and the molecular mechanism of their joint regulation of rice blast resistance
    .

    Through transcriptome sequencing analysis of rice infected with oryzae oryzae, this study identified a GRAS gene, OsSCL7, which was induced and expressed by oryzae oryzae infection
    .

    Knockout of OsSCL7 in wild-type rice attenuated M.
    oryzae resistance, while overexpression of OsSCL7 enhanced M.
    oryzae resistance
    .

    Further studies found that OsSCL7 directly interacted with the 14-3-3 protein GF14c, and knockout of GF14c enhanced the susceptibility of rice to M.
    , indicating that GF14c regulates the stability of OsSCL7 protein
    .

    In addition, OsSCL7 protein has transcriptional activation activity in vitro, and transcriptome sequencing analysis of osscl7 mutants revealed that loss of function of OsSCL7 affected the expression of a series of defense genes
    .

    This study clarifies that the rice 14-3-3 protein GF14c affects the rice blast resistance by regulating the stability of OsSCL7 in plants, providing new clues for understanding how GRAS protein participates in plant immune regulation
    .

    Link to the original text: https://onlinelibrary.
    wiley.
    com/doi/10.
    1111/pce.
    14278 The forefront of plant science, focusing on the frontier progress of plant science, the release of information, recruitment information, and the sharing of method software
    .

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