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The relationship between serum vitamin D status and antiepileptic therapy in Chinese pediatric epilepsy patients

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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Research Objectives:

Compare serum 25-OH-VitD levels in healthy children and children with epilepsy before and during treatment with antiepileptic drugs (ASMs), which is a major marker of vitamin D (VitD) status, and assess potential influencing factors
for 25-OH-VitD levels.

For comparison, we finally registered and collected data from 6,338 healthy children and 648 primary care pediatricians with epilepsy symptoms at the Children's Hospital of Nanjing Medical University from January 2019 to June 2021
.

Results of the study:

The serum 25-OH-VitD level was significantly lower in 648 children with epilepsy than in 6338 healthy children (P<0.

In this retrospective study, childhood epilepsy before and during the start of treatment with ASMs reduced serum concentrations of 25-OH-VitD, suggesting a clear link
between the risk of epilepsy and VitD deficiency.

References:

Dong N, Guo HL, Hu YH, Yang J, Xu M, Ding L, Qiu JC, Jiang ZZ, Chen F, Lu XP, Li XN.

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