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The Production Process of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine
In the chemical industry, the production of a new compound requires a complex and meticulous process that involves several steps, starting from the synthesis of the precursor molecules and ending with the isolation and purification of the final product.
The production process of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine, a new anti-inflammatory and analgesic drug, is a good example of this process.
In this article, we will discuss the various steps involved in the production of this drug.
- Synthesis of Precursor Molecules
The production of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves the synthesis of several precursor molecules.
These precursor molecules are synthesized using a variety of chemical reactions and techniques, such as alkylation, nitration, substitution, and condensation reactions.
The precursor molecules are then purified and characterized to ensure their purity and identity. - Synthesis of the Pyrazol-1-yl Moiety
The next step in the production of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves the synthesis of the pyrazol-1-yl moiety.
This is achieved by heating a mixture of the precursor molecules in a suitable solvent under controlled conditions.
The reaction mixture is then cooled and the solvent is removed, leaving behind the pyrazol-1-yl moiety, which is then purified and characterized. - Synthesis of the Amino Moiety
The next step in the production of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves the synthesis of the amino moiety.
This is achieved by reacting the pyrazol-1-yl moiety with an amino acid or a derivative of an amino acid in the presence of a suitable catalyst.
The reaction mixture is then purified and characterized to ensure the presence of the desired product. - Synthesis of the Dimethylamino Moiety
The final step in the production of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves the synthesis of the dimethylamino moiety.
This is achieved by exposing the amino moiety to a suitable reagent in the presence of a suitable catalyst.
The reaction mixture is then purified and characterized to ensure the presence of the desired product. - Purification and Characterization of the Final Product
The final step in the production of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves the purification and characterization of the final product.
This is achieved by various techniques, such as crystallization, chromatography, and spectroscopy.
The purified and characterized product is then tested for its biological activity and quality.
In conclusion, the production process of tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)-c]-pyrazol-1-yl]-amine involves several steps, starting from the synthesis of precursor molecules and ending with the purification and characterization of the final product.
The steps involved in this process require a high degree of precision and control, and are carried out in a controlled environment to ensure the purity and quality of the final product.
The production of this drug is a complex and challenging process, but it represents an important step in the development of new anti-inflammatory and analgesic drugs for