echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Antitumor Therapy > The Production Process of Tegafur

    The Production Process of Tegafur

    • Last Update: 2023-05-12
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Technetium 99m (Tc-99m) is a commonly used radioisotope in medical imaging and it is produced by the reaction of molybdenum-99 (Mo-99) with technetium-99m pertechnetate (TcO4-) in the production process known as the Tc-99m Generator.
    Technetium-99m is a short-lived isotope with a half-life of about 6.
    7 hours and it decays into rhenium-187 (Re-187) and technetium-99 (Tc-99) which is still radioactive.


    The production process of Tc-99m starts with the irradiation of natural moissanite (89Zr + n → 93Mo + 2.
    17 MeV) in a nuclear reactor to produce molybdenum-99.
    The Mo-99 is then purified and stored in a generator, typically made of stainless steel or titanium, until it is needed for use in medical imaging.
    The generator is designed to separate the Tc-99m from the Mo-99 by passing aolybdene solution through the generator.
    The aolybdene solution is composed of ammonium molybdate and hydrochloric acid and it is used to dissolve the Mo-99 and form Tc-99m.


    The Tc-99m generator is typically composed of an anode and a cathode, with anolyte solution being circulated through the anode and cathode.
    The anode is made of a material that is not reactive with Tc-99m and is typically made of stainless steel or titanium, while the cathode is made of a material that is reactive with Tc-99m, typically a noble metal such as platinum.
    The Tc-99m pertechnetate is formed at the cathode by the reaction of Tc-99 with the aolybdene solution and it is then continuously removed from the generator by a vacuum pump.


    The Tc-99m generator is typically used for medical imaging for several weeks before it needs to be reloaded with new Mo-99.
    The generator is then emptied and cleaned, and the process is repeated.
    It's important to note that the Tc-99m generator should be handled by trained personnel and must be operated in accordance with the manufacturer's instructions.


    In summary, the production process of Tc-99m involves the irradiation of natural moissanite in a nuclear reactor to produce molybdenum-99, which is then purified and stored in a Tc-99m generator.
    The generator is designed to separate Tc-99m from the Mo-99 by passing an aolybdene solution through the generator, where the Mo-99 is dissolved and form Tc-99m and other radioisotopes.
    The Tc-99m generator is typically composed of an anode and a cathode, with the anode made of a material that is not reactive with Tc-99m and circulates the aolybdene solution and the cathode made of a material that is reactive with Tc-99m.
    The Tc-99m generator is typically used for medical imaging for several weeks before it needs to be reloaded with new Mo-99.


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.