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    Home > Active Ingredient News > Drugs Articles > The Production Process of N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide

    The Production Process of N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide

    • Last Update: 2023-05-10
    • Source: Internet
    • Author: User
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    N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide, also known as Compound X, is an antibiotic substance that is currently used in the production process of some pharmaceutical drugs.
    The compound is synthesized through a multi-step process that involves several chemical reactions and purification steps.


    The production process of N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide can be divided into several stages, including the preparation of starting materials, the initial reactions, and the purification of the final product.


    1. Preparation of starting materials
      The production of N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide requires a number of starting materials, including 8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid, acetyl chloride, and sodium hydroxide.
      These starting materials are typically obtained through chemical synthesis or extraction from natural sources.
    2. Initial reactions
      The initial reaction in the production of N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide involves the reaction of 8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid and acetyl chloride in the presence of a solvent, such as dichloromethane or ethyl acetate.
      This reaction leads to the formation of an acetylated derivative of the starting material.
    3. Purification of the intermediate product
      The intermediate product obtained from the initial reaction is typically purified through several techniques, including filtration, precipitation, and chromatography.
      This purification step is important to remove any impurities that may have been introduced during the reaction, and to obtain a pure sample of the intermediate product.
    4. Final reactions
      The final reactions in the production of N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide involve the reaction of the purified intermediate product with sodium hydroxide and a reducing agent, such as hydrogen gas or sodium borohydride.
      These reactions lead to the formation of the final product, N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide.
    5. Purification and isolation of the final product
      The final product is typically purified and isolated through several techniques, including filtration, precipitation, and chromatography.
      This purification step is important to remove any impurities that may have been introduced during the final reactions, and to obtain a pure sample of the final product.

    The production process of N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide involves several chemical reactions and purification steps.
    The production of this compound requires the use of several starting materials and the implementation of various purification techniques to obtain a pure sample of the final product.
    The quality of the starting materials and the purity of the final product are critical factors that can affect the efficacy and safety of the final pharmaceutical product.


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