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Ethyl 1-((pyridin-4-yl)methyl) piperidine-4-carboxylate, also known as EPP-103, is a synthetic compound that is used in various applications in the chemical industry.
Its production process involves several steps, which are described below.
Step 1: Synthesis of Pyridine-4-carboxylic acid
The synthesis of pyridine-4-carboxylic acid involves the reaction of pyridine-4-amine with carbon dioxide in the presence of an acid catalyst, such as hydrochloric acid.
This reaction results in the formation of the pyridine-4-carboxylic acid, which is then used as a starting material for the synthesis of EPP-103.
Step 2: Synthesis of 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylic acid
The synthesis of 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylic acid involves the reaction of 1-((pyridin-4-yl)methyl) amine with pyridine-4-carboxylic acid in the presence of a strong acid catalyst, such as sulfuric acid.
This reaction results in the formation of 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylic acid, which is then used as a starting material for the synthesis of EPP-103.
Step 3: Synthesis of Ethyl 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylate
The synthesis of ethyl 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylate involves the reaction of 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylic acid with ethyl bromide in the presence of a catalyst, such as aluminum chloride.
This reaction results in the formation of ethyl 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylate, which is then purified and used as the final product.
Overall, the production process of EPP-103 involves several steps, starting from the synthesis of pyridine-4-carboxylic acid and ending with the synthesis of ethyl 1-((Pyridin-4-yl)methyl) piperidine-4-carboxylate.
Each step requires careful monitoring and control to ensure that the product meets the desired specifications and quality standards.
Additionally, the use of appropriate safety equipment and protocols is crucial to prevent accidents and injuries during the production process.
