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    Home > Active Ingredient News > Drugs Articles > The Production Process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde

    The Production Process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde

    • Last Update: 2023-05-11
    • Source: Internet
    • Author: User
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    The production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde, also known as (E)-3-[2-(7-Cl-2H-quinolin-2-yl)-2-buten-1-yl]benzaldehyde, is a multi-step process that involves several chemical reactions and purification steps.
    The final product is a synthetic chemical that is used in various applications, including as an intermediate in the production of pharmaceuticals, agrochemicals, and other industrial chemicals.


    The production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde can be broken down into the following steps:


    1. Preparation of the starting materials
      The production of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde begins with the preparation of the starting materials.
      The two key starting materials required for the synthesis of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde are 2-buten-1-yl chloride and 2-amino-7-chloro-2H-quinoline-3-carboxylate.
    2. Condensation reaction
      The next step in the production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde is a condensation reaction between 2-buten-1-yl chloride and 2-amino-7-chloro-2H-quinoline-3-carboxylate.
      This reaction involves the elimination of water and the formation of a new bond between the two starting materials to form 2-(2-buten-1-yl-7-chloro-2H-quinolin-3-yl)amino-N-(2,2-dimethyl-5,6,7,8-tetrahydroimidazo[1,2-d][1,4]benzoxazepin-9-yl)acetamide.
    3. Hydrolysis reaction
      The next step in the production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde is a hydrolysis reaction, which involves the decomposition of the intermediate molecule from step 2 using a strong acid catalyst.
      The hydrolysis reaction results in the formation of 2-(2-buten-1-yl-7-chloro-2H-quinolin-3-yl)amino-N-(2,2-dimethyl-5,6,7,8-tetrahydroimidazo[1,2-d][1,4]benzoxazepin-9-yl)acetic acid.
    4. Cyclization reaction
      The final step in the production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde is a cyclization reaction, which involves the conversion of the intermediate molecule from step 3 to (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde.
      This reaction is typically carried out using a strong acid catalyst, such as hydrochloric acid, and results in the formation of the final synthetic chemical product.

    Overall, the production process of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde involves several chemical reactions and purification steps, which require specialized equipment and a controlled environment to ensure the high quality of the final product.
    The steps involved in the production process can be optimized to reduce costs and improve efficiency, while maintaining the quality of the synthetic chemical product.


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