The Production Process of 7-BroMoisoquinoline hydrochloride

7-Bromo-1H-isoquinoline-2,3-dione hydrochloride, commonly referred to as 7-BroMoisoquinoline hydrochloride, is a chemical compound that is widely used in the pharmaceutical and agrochemical industries.
The compound is an important intermediate in the production of various medicines, including anti-inflammatory and anti-bacterial drugs.
The production process of 7-BroMoisoquinoline hydrochloride involves several steps, starting from the synthesis of the starting material to the final product.

1. Synthesis of the starting material: The starting material for the production of 7-BroMoisoquinoline hydrochloride is 1H-isoquinoline-2,3(1H,3H)-dione.
   This compound is synthesized by the reaction of 2,3-dimethyl-1,4-benzenediol with chloroform in the presence of anhydrous sodium carbonate.
   The reaction is carried out in a well-ventilated area, and the product is isolated by filtration and washed with water.
   
2. Bromination of the starting material: The next step in the production of 7-BroMoisoquinoline hydrochloride is the bromination of the starting material.
   This is achieved by the reaction of the starting material with hydrogen bromide in the presence of acetic acid.
   The reaction is carried out in a round-bottomed flask, and the product is isolated by filtration and recrystallization.
   
3. Hydrochlorination of the brominated product: The brominated product obtained in the previous step is then hydrochlorinated to obtain 7-BroMoisoquinoline hydrochloride.
   This is achieved by the reaction of the brominated product with hydrogen chloride in the presence of a catalyst, such as zinc chloride.
   The reaction is carried out in a well-ventilated area, and the product is isolated by filtration and washed with water.
   
4. Purification of the product: The final step in the production of 7-BroMoisoquinoline hydrochloride is the purification of the product.
   This is achieved by recrystallization, which involves dissolving the product in a solvent, such as ethanol or methanol, and allowing it to crystallize out.
   The crystals are then collected and washed with a solvent, such as water, to remove any impurities.
   
5. Commercial production: 7-BroMoisoquinoline hydrochloride can be produced on a commercial scale using the above steps.
   The production process is carried out in a well-ventilated area, and the reactions are performed using standard laboratory equipment, such as round-bottomed flasks, filtration sets, and recrystallization plates.
   The product is isolated by filtration and washed with solvents.
   The final product is then dried and packaged for commercial use.
   

In summary, the production process of 7-BroMoisoquinoline hydrochloride involves several steps, including the synthesis of the starting material, bromination, hydrochlorination, purification, and commercial production.
The product is widely used in the pharmaceutical and agrochemical industries and is an important intermediate in the production of various medicines.
The production process involves the use of standard laboratory equipment and is carried out in a well-ventilated area.