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The production process of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is an important industrial process that is used to produce this important intermediate for the production of various chemical products.
This compound is widely used in the production of pharmaceuticals, agrochemicals, and other industrial chemicals.
The production process of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is a multi-step process that involves several different chemical reactions and purification steps.
The first step in the production of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is the synthesis of the starting material, 4,5-dichloro-3-hydroxy-2-benzaldehyde.
This compound is synthesized by a series of chemical reactions that involve the reaction of benzaldehyde with chlorine gas in the presence of a catalyst.
The reaction is catalyzed by a Lewis acid catalyst, such as aluminum chloride, to produce the desired starting material.
The next step in the production of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is the bromination of 4,5-dichloro-3-hydroxy-2-benzaldehyde to produce the desired product.
This is typically done by using hydrogen bromide gas in the presence of a solvent, such as acetic acid.
The reaction is typically carried out at a temperature of 50-60 degrees Celsius and is allowed to proceed for several hours until the desired product is produced.
After the bromination step, the product is typically purified by crystallizing it from a solvent, such as ethanol.
The crystals are then collected and dried to remove any remaining impurities.
The purified product is then used as the starting material for the next step in the production process.
The final step in the production of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is the oxidation of the starting material to produce the desired product.
This step is typically carried out by using a strong oxidizing agent, such as potassium permanganate, in the presence of a solvent, such as water or ethanol.
The reaction is typically carried out at a temperature of 50-60 degrees Celsius and is allowed to proceed for several hours until the desired product is produced.
After the oxidation step, the product is typically purified by crystallizing it from a solvent, such as ethanol.
The crystals are then collected and dried to remove any remaining impurities.
The purified product is then used as the final product for various industrial applications.
In conclusion, the production process of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is a multi-step process that involves several different chemical reactions and purification steps.
The process typically starts with the synthesis of the starting material, 4,5-dichloro-3-hydroxy-2-benzaldehyde, and ends with the production of the desired product through a series of chemical reactions and purification steps.
The production process of 6-bromo-4,5-dichloro-3(2H)-pyridazinone is an important industrial process that is widely used in the production of various chemical products, including pharmaceuticals, agrochemicals, and other industrial chemicals.