The Production Process of 6''-AMINO-1,2,3,4-TETRAHYDROQUINOLINE

The production process of 6''-amino-1,2,3,4-tetrahydropyridine (6''-AMINO-THP) is an important step in the chemical industry, as this compound has a wide range of applications in various fields.
One of the most common applications of 6''-AMINO-THP is as a starting material for the production of dyes, pharmaceuticals, and other chemical products.

The production process of 6''-AMINO-THP typically involves several steps, starting with the synthesis of the intermediate compound 6-chloro-1,2,3,4-tetrahydropyridine.
This compound is then treated with a basic solution, followed by hydrolysis, to produce 6''-amino-1,2,3,4-tetrahydropyridine.

The first step in the production process is the synthesis of 6-chloro-1,2,3,4-tetrahydropyridine, which is done by reacting 1,2,3,4-tetrahydroquinoline with chloroform.
This reaction is carried out in the presence of a catalyst, such as aluminum chloride, to increase the reaction rate.
The resulting 6-chloro-1,2,3,4-tetrahydropyridine is then purified by crystallization or filtration to remove any impurities.

The next step in the production process is the treatment of 6-chloro-1,2,3,4-tetrahydropyridine with a basic solution, such as sodium hydroxide.
This treatment results in the conversion of 6-chloro-1,2,3,4-tetrahydropyridine into 6''-amino-1,2,3,4-tetrahydropyridine.
The reaction is typically carried out under conditions that ensure the complete conversion of 6-chloro-1,2,3,4-tetrahydropyridine, with careful monitoring of the pH and temperature to avoid any unwanted side reactions.

After the treatment with basic solution, the product is then hydrolyzed by treating with water to remove the chloride group.
This step is done to ensure the complete removal of the chloride group, which is not compatible with the subsequent reactions.

The final product is then purified by recrystallization or chromatography to remove any impurities and to obtain a pure sample of 6''-AMINO-THP.
This purified sample is then used as a starting material for the production of various chemical products, such as dyes, pharmaceuticals, and other fine chemicals.

In conclusion, the production process of 6''-amino-1,2,3,4-tetrahydropyridine involves several steps, starting with the synthesis of 6-chloro-1,2,3,4-tetrahydropyridine and ending with the purification of the final product.
The process requires careful monitoring of the reaction conditions to ensure the complete conversion of the starting material and the absence of unwanted side reactions.
The purified product is then used as a starting material for the production of various chemical products.