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    Home > Medical News > Medical World News > The Production Process of 6,8-DIMETHOXY-4-METHYLQUINOLINE

    The Production Process of 6,8-DIMETHOXY-4-METHYLQUINOLINE

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    6,8-Diemethoxy-4-methylquinoline is an organic compound that is widely used in various industries, including the chemical, pharmaceutical, and agricultural industries.
    It is a versatile compound that can be used in the production of various products, and its production process involves several steps that require careful attention to detail.


    Step 1: Synthesis of N-phenyl-N-methyl-2-amino-6,8-diemethoxy-4-methylquinoline
    The first step in the production of 6,8-diemethoxy-4-methylquinoline involves the synthesis of N-phenyl-N-methyl-2-amino-6,8-diemethoxy-4-methylquinoline.
    This compound is synthesized by reacting N-phenyl-N-(2-aminoethyl)-2-bromo-4-methylquinoline with sodium hydroxide and then treating the resulting product with 1,2-diamino-3,4-dihydroquinoline.


    Step 2: Hydrolysis of N-phenyl-N-methyl-2-amino-6,8-diemethoxy-4-methylquinoline
    After synthesizing N-phenyl-N-methyl-2-amino-6,8-diemethoxy-4-methylquinoline, the next step is to hydrolyze it using hydrochloric acid.
    This step breaks down the amide group in the compound, resulting in the formation of the corresponding carboxylic acid.


    Step 3: Condensation of N-phenyl-N-methyl-2-carboxy-6,8-diemethoxy-4-methylquinoline with 2-amino-4-methyl-6-chloro-s-triazine
    The next step in the production of 6,8-diemethoxy-4-methylquinoline is the condensation of N-phenyl-N-methyl-2-carboxy-6,8-diemethoxy-4-methylquinoline with 2-amino-4-methyl-6-chloro-s-triazine.
    This reaction involves the formation of a new bond between the carboxylic acid group and the amino group, resulting in the formation of a new compound.


    Step 4: Nitration of the new compound
    The new compound that is formed in the previous step is then nitrated using nitric acid.
    This step introduces nitro groups into the compound, which can be further transformed into other groups through later reactions.


    Step 5: Condensation of N-phenyl-N-methyl-2-amino-6-nitro-8-diemethoxy-4-methylquinoline with N-(2-hydroxyethyl)thiourea
    The next step in the production of 6,8-diemethoxy-4-methylquinoline is the condensation of N-phenyl-N-methyl-2-amino-6-nitro-8-diemethoxy-4-methylquinoline with N-(2-hydroxyethyl)thiourea.
    This reaction involves the formation of a new bond between the amino group and the thiourea group, resulting in the formation of a new compound.


    Step 6: Decomposition of N-phenyl-N-methyl-2-amino-6-nitro-8-diemethoxy-4-methylquinoline
    The final step in the production of 6,8-diemethoxy-4-methylquinoline is the decomposition of N-phenyl-N-


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