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    Home > Medical News > Medical World News > The Production Process of 6,7-Dichloroquinoline

    The Production Process of 6,7-Dichloroquinoline

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    6,7-Dichloroquinoline is an important organic compound that is widely used in the pharmaceutical, agrochemical, and other industries.
    The production process of 6,7-dichloroquinoline involves several steps, which are explained below in detail.


    1. Raw material preparation: The raw materials required for the production of 6,7-dichloroquinoline are chlorine, benzene, and quinoline.
      The chlorine and benzene are mixed together to form chlorobenzene, which is then reacted with quinoline in the presence of a catalyst to form 6,7-dichloroquinoline.
    2. Chlorination of benzene: Chlorine is added to benzene in the presence of a catalyst, such as aluminum chloride, to form chlorobenzene.
      The reaction takes place at a temperature of 80-100°C and a pressure of 5-10 atm.
    3. Quinolination of chlorobenzene: Quinoline is added to chlorobenzene in the presence of a catalyst, such as powdered zinc, to form 6,7-dichloroquinoline.
      The reaction takes place at a temperature of 150-180°C and a pressure of 5-10 atm.
    4. Purification: The product obtained from the reaction is purified by recrystallization.
      The crude product is dissolved in a solvent, such as ethyl acetate, and the crystals are allowed to form by slowly cooling the solution.
      The crystals are then collected and dried to yield pure 6,7-dichloroquinoline.
    5. Characterization: The purified 6,7-dichloroquinoline is characterized by various physico-chemical tests, such as melting point, boiling point, density, and solubility.
    6. Production scale-up: The production process of 6,7-dichloroquinoline can be scaled up by using larger reaction vessels, increasing the amount of reactants, and using more efficient mixing devices.
    7. Hazard and safety precautions: During the production of 6,7-dichloroquinoline, proper safety precautions should be taken to avoid accidents and to protect the environment.
      The workers should wear appropriate protective gear, such as gloves, safety glasses, and respirators.
      The reactants and products should be handled with care, and the waste products should be disposed of properly.

    In conclusion, the production process of 6,7-dichloroquinoline involves several steps, which can be carried out on a large scale by using appropriate equipment and safety precautions.
    The purified product can be used in various applications in the pharmaceutical, agrochemical, and other industries.


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