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    Home > Medical News > Medical World News > The Production Process of 5-Trifluoromethyl-2H-pyridazine-2-one

    The Production Process of 5-Trifluoromethyl-2H-pyridazine-2-one

    • Last Update: 2023-05-07
    • Source: Internet
    • Author: User
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    The 5-Trifluoromethyl-2H-pyridazine-2-one is an important intermediate in the production of a variety of pharmaceuticals, agrochemicals, and other chemical products.
    The production process of this compound involves several steps, which are carried out in a chemical plant.


    1. Synthesis of 2-Aminopyridine
      The production of 5-Trifluoromethyl-2H-pyridazine-2-one begins with the synthesis of 2-Aminopyridine, which is a key intermediate.
      This compound is synthesized by reducing 2-Chloropyridine with a reducing agent such as hydrazine.
      The reaction is carried out in the presence of a catalyst, such as iron or copper, to promote the reaction.
    2. Hydrochloric acid treatment
      The 2-Aminopyridine obtained from the previous step is treated with hydrochloric acid to remove any impurities.
      This step also helps to increase the purity of the compound.
      The reaction is carried out in a reaction vessel, and the mixture is stirred for a specific period.
    3. N-Bromosuccinimide treatment
      The compound obtained from the previous step is treated with N-Bromosuccinimide in the presence of a solvent such as acetonitrile.
      The reaction is carried out at a specific temperature and for a specific duration to obtain the desired product.
    4. Cooling
      The reaction mixture obtained from the previous step is cooled to room temperature.
      This step is important as it helps to prevent any further reactions from occurring.
    5. Filtration and Purification
      The mixture obtained from the previous step is filtered to remove any impurities.
      The filtrate is then purified using a suitable purification method, such as recrystallization or chromatography.
      This step is important as it helps to obtain a pure sample of the compound for further use.
    6. Characterization
      The final product obtained from the previous step is characterized to confirm its purity and identity.
      This is done using various analytical techniques, such as spectroscopy or chromatography.
    7. Packaging and Shipping
      The final product is packaged in suitable containers to protect it from moisture and other environmental factors.
      The product is then shipped to various destinations, such as pharmaceutical companies or research institutions, for further use.

    In conclusion, the production process of 5-Trifluoromethyl-2H-pyridazine-2-one involves several steps, which are carried out in a chemical plant.
    The process involves the synthesis of 2-Aminopyridine, its treatment with hydrochloric acid, N-Bromosuccinimide treatment, cooling, filtration and purification, characterization, and packaging and shipping.
    The process is carried out under controlled conditions to obtain a pure sample of the compound for further use in various industries.


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