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    Home > Medical News > Medical World News > The Production Process of 5-Bromo-4,6-dichloropyrimidine

    The Production Process of 5-Bromo-4,6-dichloropyrimidine

    • Last Update: 2023-05-09
    • Source: Internet
    • Author: User
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    The production process of 5-bromo-4,6-dichloropyrimidine is a complex multi-step process that involves several chemical reactions.
    The production process can be broken down into the following stages:


    1. Preparation of the starting material: The production of 5-bromo-4,6-dichloropyrimidine begins with the preparation of the starting material, which is 4,6-dichloropyrimidine-2,5-diamine.
      This compound is synthesized by a series of chemical reactions, including the condensation of anthranilic acid with ammonia and the cyclization of the resulting product.
    2. Bromination of 4,6-dichloropyrimidine-2,5-diamine: The next step in the production of 5-bromo-4,6-dichloropyrimidine is the bromination of 4,6-dichloropyrimidine-2,5-diamine.
      This is typically done using hydrogen bromide in the presence of a solvent, such as acetic acid or water.
    3. Reduction of the bromide: The brominated compound is then reduced to form 5-bromo-4,6-dichloropyrimidine.
      This is typically done using a reducing agent, such as lithium aluminum hydride or hydrogen in the presence of a solvent, such as ether or THF.
    4. Purification and isolation: The final step in the production of 5-bromo-4,6-dichloropyrimidine is the purification and isolation of the product.
      This is typically done by crystallization or chromatography, which allows the pure product to be isolated from any impurities that may have been present in the reaction mixture.

    The production of 5-bromo-4,6-dichloropyrimidine is a complex and multi-step process that requires a significant amount of expertise and specialized equipment.
    The process also involves the use of several hazardous chemicals, which requires the use of appropriate safety measures to ensure the safety of the workers and the environment.


    In conclusion, the production process of 5-bromo-4,6-dichloropyrimidine involves several chemical reactions and requires a significant amount of expertise and specialized equipment.
    The process is also hazardous and requires the use of appropriate safety measures to ensure the safety of the workers and the environment.
    As with any chemical production process, it is important to follow all appropriate safety guidelines and regulations to minimize the risks associated with the production and use of this compound.


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