The Production Process of 4-Pyridazinecarboxylic acid, 3-amino-, methyl ester

The production process of 4-pyridazinecarboxylic acid, 3-amino-, methyl ester involves a series of chemical reactions that convert raw materials into the desired product.
The process can be broken down into several steps, each of which involves a specific reaction or combination of reactions.
The following is a detailed explanation of the production process for 4-pyridazinecarboxylic acid, 3-amino-, methyl ester.

Step 1: Synthesis of 3-amino-1,2,4-trizine
The first step in the production of 4-pyridazinecarboxylic acid, 3-amino-, methyl ester involves the synthesis of 3-amino-1,2,4-trizine.
This compound is synthesized by reacting 2,4,6-triamino-1,3-benzenetricarboxylic acid with formaldehyde in the presence of an acid catalyst such as sulfuric acid.
The reaction involves the condensation of the two compounds to form a new compound with the desired structure.

Step 2: Nitration of 3-amino-1,2,4-trizine
The next step in the production process is the nitration of 3-amino-1,2,4-trizine.
This is done by reacting the compound with nitric acid, forming 3-nitro-1,2,4-trizine.
The reaction is typically carried out in the presence of a solvent such as water or acetonitrile, and the reaction is typically catalyzed by a strong acid catalyst such as sulfuric acid.

Step 3: Hydrolysis of 3-nitro-1,2,4-trizine
The next step in the production process is the hydrolysis of 3-nitro-1,2,4-trizine.
This is done by reacting the compound with water in the presence of a catalyst such as sodium hydroxide.
The reaction involves the cleavage of the nitro group and the formation of 3-amino-1,2,4-trizine.

Step 4: Amination of 3-amino-1,2,4-trizine
The next step in the production process is the amination of 3-amino-1,2,4-trizine.
This is done by reacting the compound with methylamine in the presence of a catalyst such as sodium hydroxide.
The reaction involves the substitution of the amino group, forming 3-amino-1,2,4-trizine methyl ester.

Step 5: Esterification of 3-amino-1,2,4-trizine methyl ester
The final step in the production process is the esterification of 3-amino-1,2,4-trizine methyl ester.
This is done by reacting the compound with 4-pyridazinecarboxylic acid in the presence of an acid catalyst such as sulfuric acid.
The reaction involves the formation of an ester bond between the two compounds, forming 4-pyridazinecarboxylic acid, 3-amino-, methyl ester.

The above steps outline the production process for 4-pyridazinecarboxylic acid, 3-amino-, methyl ester.
The process involves a series of chemical reactions that convert raw materials into the desired product.
The process requires the use of various chemicals and reagents, and is typically carried out in a well-equipped chemical laboratory or plant.
The production of 4-pyridazinecarboxylic acid, 3-amino-, methyl ester is a complex process that requires careful control and monitoring of the reaction conditions to ensure the desired product is obtained.