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    Home > Active Ingredient News > Antitumor Therapy > The Production Process of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

    The Production Process of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

    • Last Update: 2023-04-25
    • Source: Internet
    • Author: User
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    4-Amino-6-methyl-1,3,5-triazine-2-ol, also known as triamine, is a versatile chemical compound that is commonly used in the production of various chemicals, pharmaceuticals, and agrochemicals.
    The production process of triamine involves a series of chemical reactions that convert raw materials into the final product.
    In this article, we will outline the production process of triamine in the chemical industry.


    Step 1: Nitration of Aniline
    The production of triamine begins with the nitration of aniline, which is a common precursor in the chemical industry.
    In this process, aniline is treated with nitric acid to produce nitroaniline, which is then treated with sulfuric acid to produce sulfonated nitroaniline.
    This intermediate is then treated with a base, such as sodium hydroxide, to produce the parent amine, which is the starting material for the production of triamine.


    Step 2: Chalcone Formation
    The parent amine is then treated with a phenol in the presence of an acid catalyst, such as sulfuric acid or phosphoric acid, to produce chalcone.
    This reaction involves the condensation of the amine and the phenol to produce the chalcone intermediate.


    Step 3: Mannich Reaction
    The chalcone intermediate is then treated with formaldehyde and a primary or secondary amine, such as methylamine or ethylamine, in the presence of a strong acid catalyst, such as sulfuric acid or phosphoric acid.
    This reaction is known as the Mannich reaction, and it involves the condensation of the chalcone, formaldehyde, and amine to produce triamine.


    Step 4: Purification
    After the production of triamine, the final product is typically purified through a series of chemical reactions and filtration steps to remove any impurities that may have been introduced during the production process.
    This purification process is essential to ensure that the final product meets the required purity standards for use in various applications.


    Step 5: Isolation and Purification
    The purified triamine is then isolated and purified through a variety of methods, depending on the intended use of the final product.
    For example, if the triamine is intended for use in the production of pharmaceuticals, it may be necessary to purify the triamine to a high level of purity, while if the triamine is intended for use in agricultural applications, a lower level of purity may be sufficient.


    In conclusion, the production of 4-amino-6-methyl-1,3,5-triazine-2-ol, or triamine, involves a series of chemical reactions that convert raw materials into the final product.
    The production process begins with the nitration of aniline, which is treated with sulfuric acid to produce sulfonated nitroaniline, which is then treated with a base to produce the parent amine.
    The parent amine is then treated with a phenol and an acid catalyst to produce chalcone, which is then treated with formaldehyde and an amine in the presence of a strong acid catalyst to produce triamine.
    The final product is then purified and isolated, depending on the intended use of the final product.


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