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    Home > Medical News > Medical World News > The Production Process of 4,5-Dihydro-6-methyl-3(2H)-pyridazinone

    The Production Process of 4,5-Dihydro-6-methyl-3(2H)-pyridazinone

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    The production process of 4,5-dihydro-6-methyl-3(2H)-pyridazinone is a complex chemical reaction that involves several steps and intermediate products.
    The process typically involves the following steps:


    1. Preparation of the starting materials: The starting materials for the production of 4,5-dihydro-6-methyl-3(2H)-pyridazinone are typically 2-methyl-3-butyl pyridine and 2-methyl-4-vinyl pyridine.
      These materials must be synthesized or obtained from a reliable supplier.
    2. Nitration: The 2-methyl-3-butyl pyridine and 2-methyl-4-vinyl pyridine are then nitrated with nitric acid to produce the corresponding nitro derivatives.
      This step generates the intermediate products 2-methyl-3-butyl-4-nitro pyridine and 2-methyl-4-vinyl-4-nitro pyridine.
    3. Ring closure: The nitro derivatives are then heated in the presence of a base, such as sodium hydroxide or potassium hydroxide, to close the nitro group and form the pyridazinone ring.
      This step generates the intermediate product 4,5-dihydro-6-methyl-3(2H)-pyridazinone.
    4. Hydrolysis: The intermediate product is then hydrolyzed with water to remove the protecting group and generate the final product, 4,5-dihydro-6-methyl-3(2H)-pyridazinone.

    The specific conditions and reagents used in each step of the production process may vary depending on the desired yield and purity of the final product.
    The reaction conditions and intermediate products can also have a significant impact on the energy consumption and ecological impact of the production process.


    One of the key challenges in the production of 4,5-dihydro-6-methyl-3(2H)-pyridazinone is achieving high yields and purity of the final product while minimizing the energy consumption and environmental impact of the production process.
    This can be achieved by carefully selecting and optimizing the reaction conditions and by using efficient and sustainable production methods.


    In summary, the production process of 4,5-dihydro-6-methyl-3(2H)-pyridazinone involves several steps and intermediate products.
    The process typically involves nitration, ring closure, and hydrolysis steps to synthesize the final product.
    The specific conditions and reagents used in each step may vary depending on the desired yield and purity of the final product.
    The reaction conditions and intermediate products can also have a significant impact on the energy consumption and ecological impact of the production process.
    The challenge in the production of this compound is to achieve high yields and purity of the final product while minimizing the energy consumption and environmental impact of the production process.


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