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    Home > Active Ingredient News > Drugs Articles > The Production Process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile

    The Production Process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile

    • Last Update: 2023-04-26
    • Source: Internet
    • Author: User
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    The production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile is a complex chemical reaction that involves several steps, starting from the synthesis of the initial reactants and ending with the formation of the final product.
    The process can be broken down into several stages, each with its own specific equipment and conditions.
    In this article, we will provide a detailed overview of the production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile, including the necessary equipment and conditions for each stage.


    Stage 1: Synthesis of the Initial Reactants
    The first step in the production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile is the synthesis of the initial reactants.
    Mo(OAc)2(4-bromophenyl) (4-bromo-2-methylphenyl)amide, which is also known as 4-bromo-2-methylphenyliodonium 4-bromo-2-methylphenoxide, is one of the reactants used in the production of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile.
    This reactant can be synthesized using several methods, including the reaction of 2-methylphenyl chloride with sodium hydroxide followed by treatment with 4-bromo-2-methylphenyl amine.
    The other reactant, 4-(4-hydroxyphenyl)benzonitrile, can be synthesized using several methods, including the reduction of salicylic acid or the reaction of phenyl aldehyde with sodium hydroxide.


    Stage 2: Nucleophilic Substitution
    The next step in the production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile is the nucleophilic substitution reaction.
    In this stage, the 4-bromo-2-methylphenyliodonium 4-bromo-2-methylphenoxide reactant is treated with 4-(4-hydroxyphenyl)benzonitrile in the presence of a solvent, such as DMF or DMSO, and a base, such as triethylamine or pyridine.
    The nucleophilic substitution reaction results in the formation of the intermediate product 4-(4-4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile, which is a key intermediate in the production of the final product.


    Stage 3: Hydrolysis
    The third step in the production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile is the hydrolysis of the intermediate product 4-(4-4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile.
    This stage involves treating the intermediate product with water in the presence of a solvent, such as ethanol or methanol, and a catalyst, such as sodium hydroxide or hydrochloric acid.
    The hydrolysis reaction results in the formation of the final product, which is a colorless liquid with a bitter taste and a floral odor.


    Overall, the production process of 4-(4-broMo-3-(hydroxyMethyl)phenoxy)benzonitrile involves several complex chemical reactions, each with its own specific equipment and conditions.
    The process starts with the synthesis of the initial reactants and ends with the formation of the final product, which is used in a variety of applications in the chemical industry.
    The exact details of the production process may vary depending on the specific production facility, the scale of production, and the intended use of the final product.
    However, the basic steps of the


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