The Production Process of 3-Pyridazinedicarboxylic Acid, 6-Amino-, Ethyl Ester in the Chemical Industry: An Overview

3-Pyridazinedicarboxylic acid, 6-amino-, ethyl ester, commonly referred to as pyrimidine-2,4-diamine monoethyl ester, is a versatile organic compound with a wide range of applications in the chemical industry.
It is used as a starting material in the production of various chemicals, such as pharmaceuticals, agrochemicals, and dyestuff intermediates.
The production process of 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester involves several steps, including the synthesis of the starting material, the reaction of the starting material with other chemicals, and the purification and isolation of the final product.

Synthesis of the Starting Material

The synthesis of 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester starts with the synthesis of its starting material, 2-(2-aminoethylamino)ethanamine.
This compound is synthesized by reacting 2-aminoethanol with ethyl chloride in the presence of a base, such as sodium hydroxide.
The reaction produces 2-(2-aminoethylamino)ethanol, which is then hydrolyzed to produce 2-(2-aminoethylamino)ethanamine.

Reaction with Ethyl Acetate

The next step in the production process of 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester is the reaction of 2-(2-aminoethylamino)ethanamine with ethyl acetate in the presence of a catalyst, such as hydrochloric acid.
This reaction results in the formation of 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester.

Purification and Isolation of the Final Product

After the reaction is complete, the 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester is purified and isolated through crystallization.
This involves cooling the reaction mixture to lower the temperature and allowing the crystals to form.
The crystals are then separated from the liquid and washed with a solvent, such as ethanol, to remove any impurities.

Overall, the production process of 3-pyridazinedicarboxylic acid, 6-amino-, ethyl ester involves several steps, including the synthesis of the starting material, the reaction of the starting material with other chemicals, and the purification and isolation of the final product.
This compound is widely used in the chemical industry and has a wide range of applications in various fields.

Applications of 3-Pyridazinedicarboxylic Acid, 6-Amino-, Ethyl Ester

3-Pyridazinedicarboxylic acid, 6-amino-, ethyl ester has a wide range of applications in the chemical industry.
It is used as a starting material in the production of various chemicals, such as pharmaceuticals, agrochemicals, and dyestuff intermediates.

Pharmaceuticals

3-Pyridazinedicarboxylic acid, 6-amino-, ethyl ester is used in the production of certain pharmaceuticals, such as ACE inhibitors and HMG-CoA reductase inhibitors.
ACE inhibitors are used to treat hypertension, heart failure, and kidney dise