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3-Chloro-6-chloromethylpyridazine is a chemical compound that is commonly used as a intermediate in the production of various industrial chemicals, drugs, and agrochemicals.
The production process of 3-Chloro-6-chloromethylpyridazine involves several steps, which are described below in detail.
- Synthesis of Pyridazine-3-carboxylic acid: The first step in the production of 3-Chloro-6-chloromethylpyridazine is the synthesis of Pyridazine-3-carboxylic acid.
This acid is synthesized by the reaction of pyridine-3-carboxaldehyde with sodium hydroxide in the presence of a solvent such as ethanol. - Chlorination of Pyridazine-3-carboxylic acid: The next step is the chlorination of Pyridazine-3-carboxylic acid to form 3-Chloro-6-chloromethylpyridazine.
This is typically done by treating the acid with chloroform and a solvent such as dichloromethane in the presence of a catalyst such as hydrochloric acid. - Purification of the product: After the chlorination step, the product is typically purified by dissolving it in a solvent such as water and then filtering the solution.
This step removes any impurities that may have been formed during the chlorination step. - Recrystallization: The purified product is then recrystallized using a solvent such as ethanol.
This step removes any remaining impurities and results in the formation of pure crystals of 3-Chloro-6-chloromethylpyridazine. - Characterization of the product: The final step is the characterization of the product.
This is typically done by establishing the physical and chemical properties of the product using techniques such as melting point, solubility, and spectroscopy.
In summary, the production of 3-Chloro-6-chloromethylpyridazine involves the synthesis of Pyridazine-3-carboxylic acid, its chlorination, purification, recrystallization, and characterization.
These steps are typically carried out in a well-equipped chemical laboratory and require the use of specialized equipment and chemicals.
The production of 3-Chloro-6-chloromethylpyridazine is a complex process that requires a high level of expertise and knowledge of chemical synthesis and purification techniques.