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Title: The Production Process of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine in the Chemical Industry
Abstract:
In this article, we will discuss the production process of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine, a key intermediate in the production of various pharmaceuticals and chemicals.
The manufacturing process involves several steps, from the synthesis of the starting materials to the purification and isolation of the final product.
In this article, we will describe the production process in detail, highlighting the important steps and challenges involved.
Introduction:
3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine is an important intermediate in the production of various pharmaceuticals and chemicals.
It is a synthetic chemical compound that is used in the production of various medications, including anti-inflammatory drugs, anti-bacterial agents, and anti-depressants.
The chemical formula of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine is C8H6ClN4.
It has a molecular weight of 180.
65 g/mol.
The production process of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine involves several steps, starting from the synthesis of the starting materials and ending with the purification and isolation of the final product.
In this article, we will discuss the production process of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine in detail, highlighting the important steps and challenges involved.
Synthesis of Starting Materials:
The synthesis of 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine requires the synthesis of several starting materials.
The starting materials are synthesized through various chemical reactions, and the selection of the starting materials depends on the production process and the desired product.
Step 1: Synthesis of 4-chloro-6-iodopyridazine
In this step, 4-iodopyridazine is treated with hydrochloric acid to convert it into 4-chloro-6-iodopyridazine.
Step 2: Synthesis of 1-methyl-1H-pyrazol-4-amine
In this step, 1,2-dimethylhydrazine is treated with hydrochloric acid to convert it into 1,2-dimethylamine.
The resulting compound is then treated with sodium hydroxide to convert it into 1-methyl-1H-pyrazol-4-amine.
Step 3: Synthesis of N-(3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazin-4-yl)cyclohexanamine
In this step, 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine is treated with cyclohexanamine to produce N-(3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazin-4-yl)cyclohexanamine.
Purification and Isolation of the Final Product:
After the synthesis of the starting materials, the final product, 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine, is purified and isolated through various methods.
The purification and isolation process is important to remove any impurities that may have been