The Production Process of 3,6-Diiodopyridazine

The production process of 3,6-diiodopyridazine involves a series of chemical reactions that convert the starting materials into the desired product.
The following is a step-by-step overview of the production process:

1. Preparation of Potassium Iodide: The first step in the production of 3,6-diiodopyridazine involves the preparation of potassium iodide.
   This is done by reacting potassium hydroxide with iodine in the presence of water.
   The reaction produces potassium iodide, which is then dried and ground to a fine powder.
   
2. Hydrolysis of Nitrilotriacetic Acid: The next step involves the hydrolysis of nitrilotriacetic acid, which is a nitrogen-containing acid.
   This is done by adding the acid to water and sodium hydroxide.
   The reaction produces nitrilotriacetamide, which is then separated and purified.
   
3. Nitration of Aniline: The next step involves the nitration of aniline, which is an aromatic amine.
   This is done by adding nitric acid to aniline in the presence of a solvent such as water or acetone.
   The reaction produces 3,6-dinitroaniline, which is then refluxed with sodium hydroxide to convert it to 3,6-diiodopyridazine.
   
4. Reduction of the Nitro Compound: The next step involves the reduction of the nitro compound to produce the final product.
   This is done by reacting the 3,6-dinitroaniline with lithium aluminum hydride in the presence of an alcohol such as methanol.
   The reaction produces 3,6-diiodopyridazine, which is then purified and isolated.
   

The Production Process in Detail:

Step 1: Preparation of Potassium Iodide

The production of 3,6-diiodopyridazine begins with the preparation of potassium iodide.
This is done by reacting potassium hydroxide with iodine in the presence of water.
The chemical equation for this reaction is:

KOH + I2 + H2O → KI + HI

The iodine is first dissolved in water, and then potassium hydroxide is added to the solution.
The reaction produces potassium iodide, which is then dried and ground to a fine powder.

Step 2: Hydrolysis of Nitrilotriacetic Acid

The next step involves the hydrolysis of nitrilotriacetic acid, which is a nitrogen-containing acid.
This is done by adding the acid to water and sodium hydroxide.
The chemical equation for this reaction is:

N(CH2CO2H)3 + H2O + NaOH → N(CH2CO2H)3·H2O + NaNO3

The reaction produces nitrilotriacetamide, which is then separated and purified.

Step 3: Nitration of Aniline

The next step involves the nitration of aniline, which is an aromatic amine.
This is done by adding nitric acid to aniline in the presence of a solvent such as water or acetone.
The chemical equation for this reaction is:

C6H5NH2 + HNO3 + solvent → C6H5NH2·HNO3

The reaction produces 3,6-dinitroaniline, which is then refluxed with sodium hydroxide to convert it to 3,6-diiodopyridazine.
The chemical equation for this reaction is:

C6H5NH2·HNO3 + NaOH → C6H12N2I2 + 2HNO3 +