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The Production Process of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide

 Last Update: 2023-05-10
 Source: Internet
 Author: User

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The Production Process of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide

In the chemical industry, the production process of a compound is a critical aspect that determines the efficiency, cost-effectiveness, and quality of the final product.
The production process of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide, a novel and potential pharmaceutical compound, is a complex process that involves several stages, including synthesis, purification, and characterization.
In this article, we will discuss the production process of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide in detail.

Synthesis

The synthesis of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide involves several steps, including the synthesis of the intermediate compounds and their subsequent modification.
The synthesis process can be divided into the following stages:

Synthesis of the starting materials: The synthesis of the starting materials, including (2S)-2-(4-hydroxyphenyl)glycyl-N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl)amide and (2R)-2-(4-hydroxyphenyl)glycyl-N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl)amide, can be achieved through various methods, such as asymmetric synthesis, enamine formation, and mono-alkylation.
Coupling reaction: The synthesis of the (2R)-2-(4-hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide compound involves a coupling reaction between the two starting materials.
The reaction conditions, such as temperature, solvent, and catalyst, should be optimized to achieve the desired yield and purity of the product.

Purification and Characterization

The purification and characterization of (2R)-2-(4-Hydroxyphenyl)glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.
2.
0]hept-6-yl]-(2R)-2-(4-hydroxyphenyl)glycinamide are critical steps in the production process.
The purification process can be divided into the following stages:

Crystallization: The first step in the purification process is crystallization.
Crystallization is a method used to separate

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