The Production Process of 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2)

The Production Process of 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2)

2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2), also known as Tranylcypromine, is a synthetic chemical compound that is commonly used as a research chemical.
It is a complex organic compound that is synthesized through a multistep process that involves several chemical reactions.
In this article, we will discuss the production process of Tranylcypromine, including the synthetic pathway, the reagents and raw materials required, and the various steps involved in the manufacturing process.

Synthetic Pathway

The synthesis of Tranylcypromine involves several steps, including the synthesis of the starting materials and the final product.
The synthetic pathway of Tranylcypromine involves the following steps:

1. Synthesis of 3,4-dimethoxyphenylacetic acid: This step involves the reaction of phenyl acetic acid with dimethoxy sulfur dioxide to form 3,4-dimethoxyphenylacetic acid.
   
2. Synthesis of 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-one: This step involves the reaction of 3,4-dimethoxyphenylacetic acid with methyl iodide and pyridine-2,5-dimethyl-1,4-benzoquinone in the presence of cesium carbonate.
   
3. Synthesis of 2,2′-(1,5-pentanediyl) dipropionic acid: This step involves the reaction of dipropionic acid with 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-one in the presence of sodium hydroxide.
   
4. Synthesis of 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2): This step involves the reaction of 2,2′-(1,5-pentanediyl) dipropionic acid with ethyl bromide in the presence of sodium hydroxide.
   

Reagents and Raw Materials

The production of Tranylcypromine requires several reagents and raw materials, including:

1. Phenyl acetic acid: This is a starting material used in the synthesis of 3,4-dimethoxyphenylacetic acid.
   
2. Dimethoxy sulfur dioxide: This is a reagent used in the synthesis of 3,4-dimethoxyphenylacetic acid.
   
3. Methyl iodide: This is a reagent used in the synthesis of 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-one.
   
4. Pyridine-2,5-dimethyl-1,4-benzoquinone: This is a reagent used in the synthesis of 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-one.
   
5. Dipropionic acid: This is a reagent used in the synthesis of 2,2′-(1,5-pentanediyl) dipropionic acid.
   
6. Ethyl bromide: This is a reagent used in the synthesis