The Production Process of 2-PYRIDYLDITHIOCARBAMIC ACID ETHYL ESTER

2-Pyridyldithiocarbamic acid ethyl ester, also known as PDCEE, is a chemical compound that is commonly used in the chemical industry as a reaction intermediate and building block for the synthesis of various chemicals and pharmaceuticals.
The production process of PDCEE involves several steps, including the synthesis of the starting material, the reaction of the starting material to form PDCEE, and the purification of the final product.

The synthesis of the starting material, 2-pyridyldithiocarbamate, is typically carried out by reacting pyridine-N-oxide with dithiocarbamic acid in the presence of a solvent, such as dichloromethane or chloroform.
The reaction is usually carried out under mildly acidic conditions, and the reaction mixture is then allowed to warm to room temperature to complete the reaction.

Once the starting material has been synthesized, it can be reacted with ethanol in the presence of a base, such as sodium hydroxide, to form PDCEE.
The reaction is typically carried out in a solvent, such as ethanol or methanol, and is typically allowed to proceed for several hours at room temperature.
The reaction can be monitored by TLC or HPLC to ensure that it is complete.

After the reaction is complete, the reaction mixture is typically quenched with water to stop the reaction, and the mixture is then extracted with a solvent, such as ether or dichloromethane, to separate the desired product from the reaction mixture.
The organic layer is then dried over anhydrous sodium sulfate and filtered, and the filtrate is then concentrated to remove the solvent.

The final step in the production process is the purification of the PDCEE.
This is typically carried out by crystallization, either from a solvent, such as ethanol or methanol, or by recrystallization from a solvent, such as ether or hexanes.
The purified PDCEE can then be collected and dried under vacuum to remove any residual solvent.

In conclusion, the production process of 2-pyridyldithiocarbamic acid ethyl ester involves several steps, including the synthesis of the starting material, the reaction of the starting material to form PDCEE, and the purification of the final product.
The process can be carried out using standard chemical reagents and equipment, and the product can be obtained in high purity by crystallization or recrystallization.
The product is widely used in the chemical industry and pharmaceuticals as a building block for the synthesis of various chemicals and pharmaceuticals.