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2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- is an organic compound that is commonly used in the chemical industry.
It is a synthetic chemical that is used as an intermediate in the production of various pharmaceuticals, agrochemicals, and other chemical products.
The compound is synthesized through a multi-step synthesis process that involves several chemical reactions and purification steps.
In this article, we will take a closer look at the production process of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)-.
Step 1: Preparation of 2-chloromethyl-1,3-oxazolidine
The first step in the synthesis of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- involves the preparation of 2-chloromethyl-1,3-oxazolidine.
This compound is synthesized by reacting methyl chloride with hydrazine in the presence of a solvent such as DMF or DMSO.
The reaction is exothermic and should be carried out with proper safety precautions.
Step 2: Hydrolysis of 2-chloromethyl-1,3-oxazolidine
In the next step, the 2-chloromethyl-1,3-oxazolidine is hydrolyzed to form 2-amino-1,3-oxazolidine.
This is typically done by treating the compound with water and a strong acid catalyst such as hydrochloric acid or sulfuric acid.
The reaction is typically carried out in a solvent such as ethyl acetate or benzene.
Step 3: Formation of 2-(2-amino-1,3-oxazolidin-4-yl)-1,3-oxazolidine
The next step in the synthesis of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- involves the formation of 2-(2-amino-1,3-oxazolidin-4-yl)-1,3-oxazolidine.
This is typically done by treating 2-amino-1,3-oxazolidine with diethyl aceti