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    Home > Active Ingredient News > Antitumor Therapy > The Production Process of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)-

    The Production Process of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)-

    • Last Update: 2023-05-11
    • Source: Internet
    • Author: User
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    2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- is an organic compound that is commonly used in the chemical industry.
    It is a synthetic chemical that is used as an intermediate in the production of various pharmaceuticals, agrochemicals, and other chemical products.
    The compound is synthesized through a multi-step synthesis process that involves several chemical reactions and purification steps.
    In this article, we will take a closer look at the production process of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)-.


    Step 1: Preparation of 2-chloromethyl-1,3-oxazolidine


    The first step in the synthesis of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- involves the preparation of 2-chloromethyl-1,3-oxazolidine.
    This compound is synthesized by reacting methyl chloride with hydrazine in the presence of a solvent such as DMF or DMSO.
    The reaction is exothermic and should be carried out with proper safety precautions.


    Step 2: Hydrolysis of 2-chloromethyl-1,3-oxazolidine


    In the next step, the 2-chloromethyl-1,3-oxazolidine is hydrolyzed to form 2-amino-1,3-oxazolidine.
    This is typically done by treating the compound with water and a strong acid catalyst such as hydrochloric acid or sulfuric acid.
    The reaction is typically carried out in a solvent such as ethyl acetate or benzene.


    Step 3: Formation of 2-(2-amino-1,3-oxazolidin-4-yl)-1,3-oxazolidine


    The next step in the synthesis of 2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, (2R,4R)- involves the formation of 2-(2-amino-1,3-oxazolidin-4-yl)-1,3-oxazolidine.
    This is typically done by treating 2-amino-1,3-oxazolidine with diethyl aceti


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