The Production Process of 2-Chloro-N-methyl-isonicotinamide

2-Chloro-N-methyl-isonicotinamide, also known as 2CI, is a popular research chemical that is used in various applications in the chemical industry.
It is a synthetic compound that is synthesized through a multi-step process involving several chemical reactions.
The production process of 2CI involves several stages, and each stage requires careful control and monitoring to ensure the quality of the final product.

Step 1: Synthesis of N-Methyl-Isonicotinamide
The first step in the production of 2CI is the synthesis of N-Methyl-Isonicotinamide, which is the starting material for the synthesis of 2CI.
This compound is synthesized by reacting methyl iodide with isonicotine hydrochloride in the presence of a solvent such as acetonitrile or DMF.
The reaction is typically carried out at room temperature, and the product is isolated by filtration and washed with water.

Step 2: Chlorination of N-Methyl-Isonicotinamide
The next step in the production of 2CI is the chlorination of N-Methyl-Isonicotinamide.
This is achieved by adding hydrogen chloride gas to a solution of N-Methyl-Isonicotinamide in a solvent such as acetonitrile or dichloromethane.
The reaction is typically carried out at low temperatures, and the product is isolated by filtration and washed with water.

Step 3: Hydrolysis of 2-Chloro-N-Methyl-Isonicotinamide
The final step in the production of 2CI is the hydrolysis of 2-Chloro-N-Methyl-Isonicotinamide.
This is achieved by adding the compound to a solution of hydrochloric acid in water, and the product is isolated by filtration and washed with water.
The final product is then dried and purified to remove any impurities.

Quality Control
The production process of 2CI requires strict quality control measures to ensure the quality of the final product.
This includes the testing of the raw materials, intermediates, and finished products for purity, stability, and other physical and chemical properties.
The process also includes monitoring the reaction conditions, such as temperature, pressure, and time, to ensure that they are within the optimal range for the synthesis of the compound.

Benefits of 2CI
2CI is a versatile compound that has a wide range of applications in the chemical industry.
It is used in various research and development projects, and it is also used as a building block for the synthesis of other compounds.
Some of the benefits of 2CI include its high purity, stability, and ease of synthesis.
It is also relatively easy to handle and store, making it a popular choice for various applications in the chemical industry.

Conclusion
The production process of 2CI is a multi-step process that requires careful control and monitoring to ensure the quality of the final product.
The compound is synthesized through a series of chemical reactions, and each step requires strict quality control measures to ensure the purity and stability of the product.
2CI is a versatile compound with a wide range of applications in the chemical industry, and its benefits include its high purity, stability, and ease of synthesis.