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    Home > Medical News > Medical World News > The Production Process of 2,4-DIAMINO-6-ETHOXYPYRIMIDINE

    The Production Process of 2,4-DIAMINO-6-ETHOXYPYRIMIDINE

    • Last Update: 2023-05-05
    • Source: Internet
    • Author: User
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    2,4-Diamino-6-ethoxypyrimidine is a synthetic organic compound that is commonly used in the chemical industry.
    Its production process involves several steps, including the synthesis of intermediates and the final product.
    In this article, we will provide a detailed overview of the production process of 2,4-diamino-6-ethoxypyrimidine.


    Step 1: Synthesis of Intermediates
    The production of 2,4-diamino-6-ethoxypyrimidine involves several intermediates, which are synthesized through various chemical reactions.
    The first intermediate is 2,4-diaminopyrimidine, which is synthesized by treating ammonia with hydrogen cyanide in the presence of a strong acid catalyst.
    The resulting product is then hydrolyzed with water to produce 2,4-diaminopyrimidine.


    Another intermediate is ethyl 2,4-diaminopentanoate, which is synthesized by reacting 2,4-diaminopyrimidine with ethyl chloride in the presence of a solvent such as ether.
    This intermediate is then converted to 2,4-diamino-6-ethoxypyrimidine through a series of chemical reactions.


    Step 2: Synthesis of 2,4-diamino-6-ethoxypyrimidine
    The synthesis of 2,4-diamino-6-ethoxypyrimidine involves several chemical reactions.
    The first step involves the reaction of ethyl 2,4-diaminopentanoate with sodium hydroxide in a solvent such as ethanol.
    This reaction results in the conversion of the ethyl ester to the corresponding amine.


    The next step involves the reaction of the amine with 3-chloro-4-fluoroaniline in the presence of a solvent such as acetonitrile.
    This reaction results in the formation of an N-substituted derivative of 2,4-diaminopyrimidine.


    The next step involves the reaction of the N-substituted derivative with epibromohydrin in the presence of a solvent such as dichloromethane.
    This reaction results in the formation of a resin that contains the desired product.


    Step 3: Purification and Characterization of 2,4-Diamino-6-Ethoxypyrimidine
    After the synthesis of 2,4-diamino-6-ethoxypyrimidine, the product must be purified and characterized to ensure its purity and identity.
    This involves several steps, including the removal of impurities such as solvents and other byproducts.


    The purified product is then characterized by various methods, including spectroscopy, chromatography, and mass spectrometry.
    These methods are used to determine the chemical structure, purity, and identity of the product.


    Overall, the production process of 2,4-diamino-6-ethoxypyrimidine involves several steps, including the synthesis of intermediates and the final product.
    The product is then purified and characterized to ensure its purity and identity.
    The production of 2,4-diamino-6-ethoxypyrimidine is a complex process that requires careful control of the synthesis and purification steps to ensure the production of a high-quality final product.


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