-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
2-(3-BroMophenyl)-9H-BroMophenylcarbazole is an important intermediate in the production of various pharmaceuticals, agrochemicals, and other industrial products.
The production process of this compound involves several steps, which are described in detail below.
Step 1: Synthesis of 3-BroMophenylamine
The synthesis of 3-BroMophenylamine involves several steps, including the nitration of aniline with nitric acid, followed by reduction of the nitro group using hydrogenation.
The resulting compound is then treated with NaOH to form the required amine.
Step 2: Synthesis of 2-(3-BroMophenyl)-9H-BroMophenylamine
The synthesis of 2-(3-BroMophenyl)-9H-BroMophenylamine involves the condensation of 3-BroMophenylamine with 9H-BroMophen-9-amine in the presence of a suitable condensing agent such as dicyclohexylcarbodiimide (DCC).
The reaction is carried out in a suitable solvent such as dichloromethane, and the resulting product is then purified by chromatography to obtain the desired compound.
Step 3: CARP Alkylation
The CARP alkylation process involves the alkylation of 2-(3-BroMophenyl)-9H-BroMophenylamine with a suitable alkylating agent such as methyl iodide or ethyl iodide in the presence of a base such as sodium hydroxide.
The reaction is carried out in a suitable solvent such as acetonitrile, and the resulting product is then purified by chromatography to obtain the desired compound.
Step 4: Deprotection
The final step in the production of 2-(3-BroMophenyl)-9H-BroMophenylcarbazole involves the deprotection of the amine group by treatment with hydrazine in a suitable solvent such as ethanol.
The resulting product is then purified by chromatography to obtain the desired compound.
Overall, the production process of 2-(3-BroMophenyl)-9H-BroMophenylcarbazole involves several steps, including the synthesis of 3-BroMophenylamine, the condensation of 3-BroMophenylamine with 9H-BroMophen-9-amine, the CARP alkylation of the resulting compound with a suitable alkylating agent, and the deprotection of the amine group by treatment with hydrazine.
The resulting compound is then purified by chromatography to obtain the desired final product.
This production process is widely used in the pharmaceutical and agrochemical industries, as well as in other industrial applications.