The Production Process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl

In the chemical industry, the production process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl is a complex and multi-step process that involves various chemical reactions and purification methods.
This article will provide a detailed overview of the production process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl.

Step 1: Synthesis of 4-(carbazol-9-yl)phenylboronic acid
The production of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl starts with the synthesis of 4-(carbazol-9-yl)phenylboronic acid.
This compound is synthesized by reacting phenylboronic acid with 9-bromocarbazole in the presence of a base such as sodium hydroxide.
The reaction is carried out in a solvent such as DMF or DMA, and the product is purified by recrystallization.

Step 2: Synthesis of 2,2'-dibromobiphenyl-4,4'-dicarboxylic acid
The next step in the production process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl is the synthesis of 2,2'-dibromobiphenyl-4,4'-dicarboxylic acid.
This compound is synthesized by reacting 2,2'-dibromobiphenyl with 4,4'-dicarboxylic acid in the presence of a catalyst such as HBF4.
The reaction is carried out in a solvent such as THF, and the product is purified by recrystallization.

Step 3: Synthesis of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl
The final step in the production process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl is the synthesis of the final product.
This is done by reacting 2,2'-dibromobiphenyl-4,4'-dicarboxylic acid with 4-(carbazol-9-yl)phenylboronic acid in the presence of a catalyst such as Pd(PPh3)4.
The reaction is carried out in a solvent such as DME, and the product is purified by recrystallization.

Quality Control

To ensure the quality of the final product, various quality control tests are conducted at each stage of the production process.
These tests include:

• Elemental analysis: This test is used to determine the elemental composition of the final product.
  
• Chromatography: This test is used to determine the purity of the final product by separating it from any impurities.
  
• Spectroscopy: This test is used to determine the structure of the final product by analyzing its spectral properties.
  

Conclusion

The production process of 2,2'-bis(4-(carbazol-9-yl)phenyl)-biphenyl is a complex and multi-step process that involves various chemical reactions and purification methods.
The quality of the final product is ensured through quality control tests conducted at each stage of the production process.
This article has provided a detailed overview of the production process, and it is important to note that the specific conditions and reagents may vary depending on the manufacturer and the scale of production.