The Production Process of [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2)

The Production Process of [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2) is an important process in the chemical industry.
It is used as an intermediate in the production of certain pharmaceuticals and agrochemicals.
The process involves several steps, including the synthesis of 2,2′-bicinnamic acid, its conversion into 2,2′-bicyclohexylcarboxylic acid, and the final conversion into [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2).
The following is an overview of the production process of [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2).

Step 1: Synthesis of 2,2′-Bicinnamic Acid

The synthesis of 2,2′-bicinnamic acid involves several steps.
The first step is the reaction of cinnamic acid with sodium carbonate, which is followed by hydrolysis with water.
The resulting product is 2,2′-bicinnamic acid, which is then isolated and purified.

Step 2: Conversion of 2,2′-Bicinnamic Acid into 2,2′-Bicyclohexylcarboxylic Acid

The next step in the production process is the conversion of 2,2′-bicinnamic acid into 2,2′-bicyclohexylcarboxylic acid.
This is achieved by the reaction of 2,2′-bicinnamic acid with cyclohexanone in the presence of a catalyst.
The resulting product is then purified and isolated.

Step 3: Conversion of 2,2′-Bicyclohexylcarboxylic Acid into [2,2′-Biquinoline]-4,4′-dicarboxylic Acid, Potassium Salt (1:2)

The final step involves the conversion of 2,2′-bicyclohexylcarboxylic acid into [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2).
This is achieved by treating 2,2′-bicyclohexylcarboxylic acid with potassium hydroxide in the presence of a solvent.
The resulting product is then purified and isolated.

Chemical Reactions Involved

The production process of [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2) involves several chemical reactions, including the following:

• Synthesis of 2,2′-bicinnamic acid from cinnamic acid and sodium carbonate
• Hydrolysis of 2,2′-bicinnamic acid with water
• Conversion of 2,2′-bicinnamic acid into 2,2′-bicyclohexylcarboxylic acid through the reaction with cyclohexanone in the presence of a catalyst
• Conversion of 2,2′-bicyclohexylcarboxylic acid into [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2) through treatment with potassium hydroxide in the presence of a solvent

Some Key Considerations

When producing [2,2′-Biquinoline]-4,4′-dicarboxylic acid, potassium salt (1:2), it is essential to consider some key factors.
These include the quality of the starting materials, the reaction conditions, and the purification and isolation processes.
Careful control of