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The production process of 2-((2-Acetamido-6-oxo-1H-purin-7(6H)-yl)methoxy)ethyl acetate, also known as AZM0501274, involves several stages, including synthesis, purification, and formulation.
Synthesis: The synthesis of 2-((2-Acetamido-6-oxo-1H-purin-7(6H)-yl)methoxy)ethyl acetate involves several steps, including the preparation of starting materials, the coupling reaction, and the protection and deprotection of theintermediate.
In the first step, the starting material 6-bromo-2-oxo-1,2,3,4-tetrahydro-QUINOLINE-7-carboxylic acid is prepared through a sequence of reactions.
This material is then treated with 2-((2-amino-5-oxo-1,2,3,4-tetrahydro-QUINOLIN-6-yl)methoxy)ethyl acetate in the presence of a catalyst, such as hydrochloric acid, to form 2-((2-Acetamido-6-oxo-1H-purin-7(6H)-yl)methoxy)ethyl acetate.
Purification: After the synthesis step, the product is extracted, washed, and concentrated.
The resulting mixture is then passed through a bed of activated carbon to remove any impurities.
The purified product is then dried and stored until the next step.
Formulation: The final step in the production process is the formulation of 2-((2-Acetamido-6-oxo-1H-purin-7(6H)-yl)methoxy)ethyl acetate into a final product, such as a pharmaceutical drug or a research chemical.
This step involves the addition of excipients, such as buffering agents, stabilizers, and preservatives, to the purified product.
Quality Control: The quality of the final product is ensured through a series of tests, including spectroscopic analysis, chromatography, and microbiological testing.
These tests are performed at various stages of the production process to ensure that the product meets the required standards for purity, identity, and potency.
Conclusion: The production process of 2-((2-Acetamido-6-oxo-1H-purin-7(6H)-yl)methoxy)ethyl acetate is a complex sequence of reactions that involves several stages, includingsynthesis, purification, and formulation.
The quality of the final product is ensured through a series of tests, and the product is packaged and stored according to strict guidelines to ensure its stability and effectiveness.
