The Production Process of 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

The production process of 1-pyrimidin-2-yl-piperidine-4-carboxylic acid ethyl ester involves several steps that require careful planning and execution.
This compound is used in various applications in the chemical industry, making its production a crucial process.

1. Raw Material Preparation
   The production process of 1-pyrimidin-2-yl-piperidine-4-carboxylic acid ethyl ester begins with the preparation of raw materials.
   The compound's working formula is C12H14N2O2, and it requires the use of several chemicals to create the final product.
   These chemicals include 2-pyrimidin-4-ylamine, ethyl bromide, and hydroxyacetic acid.
   
2. Condensation Reaction
   The next step involves the condensation reaction of 2-pyrimidin-4-ylamine and ethyl bromide in the presence of a condensation agent.
   The reaction takes place in a reaction flask, and the mixture is heated to a certain temperature to promote the reaction.
   The condensation agent used in this process can be a range of chemicals, such as pyridine or triethylamine.
   
3. Nitration Reaction
   After the completion of the condensation reaction, the compound is subjected to a nitration reaction to produce the 1-pyrimidin-2-yl-piperidine-4-carboxylic acid ethyl ester.
   This step involves the addition of nitric acid to the compound, which leads to the formation of the desired product.
   
4. Esterification Reaction
   The final step in the production process of 1-pyrimidin-2-yl-piperidine-4-carboxylic acid ethyl ester is the esterification reaction.
   This step involves the addition of hydroxyacetic acid to the compound to form the ester.
   The esterification reaction takes place in the presence of an acid catalyst, such as sulfuric acid or hydrochloric acid.
   
5. Purification and Recovery
   After the completion of the esterification reaction, the compound is purified and recovered.
   This involves the use of several techniques, such as filtration and distillation, to separate the desired product from any impurities.
   
6. Characterization and Analysis
   The final product is then characterized and analyzed to ensure that it meets the required standards for purity and quality.
   This involves the use of various techniques, such as spectroscopy and chromatography, to determine the compound's physical and chemical properties.
   

In conclusion, the production process of 1-pyrimidin-2-yl-piperidine-4-carboxylic acid ethyl ester is a multi-step process that requires careful planning and execution.
Each step must be carried out with precision to ensure that the final product meets the required standards for purity and quality.
The compound has a wide range of applications in the chemical industry, making its production a crucial process.