-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
The production process of 1-(1-HEXYL)-PIPERAZINE involves several steps, including the preparation of the starting materials, the reaction, and the purification of the final product.
The following is an overview of the production process of 1-(1-HEXYL)-PIPERAZINE.
Preparation of Starting Materials:
The starting materials for the production of 1-(1-HEXYL)-PIPERAZINE are 1-fluoro-2,3-dihydro-1H-benz[e]indole and 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium iodide (Hunig's base).
The 1-fluoro-2,3-dihydro-1H-benz[e]indole is first synthesized by a series of reactions, including the reduction of 2,3-dihydro-1H-indene-1-carboxaldehyde with lithium aluminum hydride, and the subsequent hydrolysis of the aldehyde with hydrochloric acid.
The Hunig's base is synthesized by the reaction of 2-iodxylamine with sodium hydroxide, followed by the treatment of the resulting iodide with sodium hydride.
Reaction:
The Hunig's base and 1-fluoro-2,3-dihydro-1H-benz[e]indole are reacted in the presence of a solvent such as dimethylformamide or N,N-dimethylacetamide, and a base such as sodium hydroxide or potassium hydroxide, to form 1-(1-HEXYL)-PIPERAZINE.
The reaction is typically carried out at a temperature of 120-180°C and the mixture is stirred for a period of time.
Purification:
The resulting mixture is then cooled to room temperature, and the precipitated solid is collected by filtration and washed with a solvent such as ethanol or methanol.
The solid is then dried under vacuum to remove any remaining moisture.
The purified 1-(1-HEXYL)-PIPERAZINE is then ground to a fine powder and packaged for use.
The production process of 1-(1-HEXYL)-PIPERAZINE is a multi-step process that requires the use of specialized equipment and reagents.
The production process is carried out in a controlled environment in order to ensure the quality of the final product.
The production process of 1-(1-HEXYL)-PIPERAZINE is a complex process, and it involves several steps, including the preparation of the starting materials, the reaction, and the purification of the final product.
The quality of the final product is determined by the purity, the yield, and the activity.
The purity of the
