The Production Process of 1,1'-Biphenyl]-2,2',6,6'-tetrol

The production process of 1,1'-biphenyl]-2,2',6,6'-tetrol, also known as Quick Acting Penicillin (QAP), is a complex and multi-step process that involves several chemical reactions and purification steps.
The production process of QAP can be broadly divided into four main stages: synthesis of the starting material, synthesis of 1,1'-biphenyl]-2,2',6,6'-tetrol, purification of the product, and final packaging and storage.

Synthesis of the Starting Material
The starting material for the production of 1,1'-biphenyl]-2,2',6,6'-tetrol is 2,2'-dihydroxy-5,5'-dimethyl-1,1'-biphenyl, which is synthesized from 2,2'-dimethoxy-1,1'-biphenyl and formaldehyde.
The synthesis of the starting material involves several steps, including the treatment of 2,2'-dimethoxy-1,1'-biphenyl with formaldehyde in the presence of an acid catalyst, followed by hydrolysis and purification of the product.

Synthesis of 1,1'-biphenyl]-2,2',6,6'-tetrol
The next step in the production process is the synthesis of 1,1'-biphenyl]-2,2',6,6'-tetrol, which involves several chemical reactions.
The synthesis of 1,1'-biphenyl]-2,2',6,6'-tetrol begins with the treatment of 2,2'-dihydroxy-5,5'-dimethyl-1,1'-biphenyl with chlorosulfonic acid, which leads to the formation of 2,2',6,6'-tetrachloro-1,1'-biphenyl.
This intermediate is then treated with sodium hydroxide and methanol to form 2,2',6,6'-tetraol-1,1'-biphenyl, which is then hydrogenated over palladium-on-charcoal to form 1,1'-biphenyl]-2,2',6,6'-tetrol.

Purification of the Product
The final product of the production process is a pure sample of 1,1'-biphenyl]-2,2',6,6'-tetrol, which is used as a starting material for the synthesis of Quick Acting Penicillin.
The purification of the product involves several steps, including the precipitation of the product with a suitable solvent, such as ether, and filtration of the resulting solid.
The solid is then washed with distilled water and dried, after which it is dissolved in a suitable solvent, such as methanol or ethanol, for use in the next step of the production process.

Final Packaging and Storage
The final step in the production process is the packaging and storage of the pure sample of 1,1'-biphenyl]-2,2',6,6'-tetrol.
The product is typically packaged in airtight containers to prevent degradation and stored in a cool, dry place until it is needed for further processing.

In conclusion, the production process of 1,1'-biphenyl]-2,2',6,6'-tetrol is a complex and multi-step process that involves several chemical reactions and purification steps.
The process begins with the synthesis of the starting material, followed by the synthesis of 1,1'-biphenyl]-2,2',6,6'-tetrol, purification of the product, and final packaging and storage.
The production of 1,1'-biphenyl]-2,2',6,6'-tetrol is an important process in the chemical industry, as the product is used as a starting material for the synthesis of Quick Acting Penicillin, which is an important antibiotic used to treat a range of bacterial infections.