The pressure is so great that I can't sleep... The consequences may be worse than you might think, new research suggests.

Lying in bed, clearly very tired, but, think of the project dead line, unfinassed KPIs or anxious news, huge pressure to make people sleepless ... If you've ever had that experience, you're not alone.
studies have found that stress is closely related to sleep problems.
recently, scientists found key neurons in the brain that "stress causes insomnia," according to a new study published in Science Advances, a sub-journal of science.
researchers at Stanford University and Cold Spring Harbor Laboratory found a direct link between stress-sensitive nerve cells and nerve cells that cause insomnia when under chronic stress.
, this set of neural loops also causes changes in the immune system... For the study, scientists first created an environment in the lab that put mice under chronic stress.
then, they focused on neuron activity in the lower hyalural glyceral bypass (PVN) and the outer side of the hyalural brain (LH), two brain regions that are often associated with stress, sleep,/ awakening.
found that neurons associated with stress-triggering hormones in the PVN brain region directly dominate the neurons in the LH brain region that cause awakening.
does that mean? The researchers tested that when the connection between the two groups of neurons was artificially interrupted, the mice in a stressful environment were able to sleep peacefully, and instead, using photogenetics techniques to artificially activate the neural loop, the mice lost sleep and woke up quickly, even if they were already asleep.
" this set of neural loops is like a particularly sensitive switch, with a slight stimulation leading to insomnia.
Jeremy Borniger, one of the authors of the study, concluded.
, however, when you turn on this neural switch, the consequences are not just innowing.
used single-cell mass spectrometrography (CyTOF) to analyze immune cells in the blood.
they were surprised to find that after stimulating the corresponding neurons in the PVN brain region of mice, there were extensive and significant changes in natural killer cells, B cells, T cells and other immune cells in the blood during insomnia in mice.
addition to the number of distributions, the signaling path paths within immune cells related to proliferative, survival, mobilization and other functions have also changed.
changes in the immune system mean that the body's defenses against threats will be weakened.
caused by stress are common and often occur the next day when there are important tasks or dead lines approaching.
" Professor Borniger said, "And clinically, it has long been noted that patients who are under pressure for a long time tend to be less responding to a variety of therapies and are prone to a variety of diseases."
"Now, researchers hope to find effective ways to prevent stress from damaging health by revealing the mechanisms behind it, opening the door to an in-depth understanding of the consequences of stress."
Borniger said: "Inflammatory bowel disease and cancer are all associated with systemic inflammation, and if we can understand and regulate the immune system from a neurore loop perspective, I believe it will be more effective in the long run."
" and for us, knowing that stress not only causes insomnia, but also changes in immune cells throughout the body, it's imperative to try to relax yourself, such as dim lighting, putting down your phone, and getting ready for a good night's sleep.
stressful things and wait until you wake up and think about them.
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