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The overall cardiovascular risk of gestational diabetes may increase by 40% |
Recently, a large-scale cohort study of 1002486 patients in the field of cardiovascular disease and health by Professor Yu Yongfu’s group from the School of Public Health of Fudan University and Professor Jiong Li’s group from Aarhus University in Denmark showed that the overall risk of cardiovascular disease in patients with gestational diabetes Increase by 40%
.
Related results have been published in "Diabetes Care"
A large population cohort study involving 1002486 patients in the field of cardiovascular disease and health by Yu Yongfu’s group and Jiong Li’s group at Aarhus University in Denmark showed that the overall risk of cardiovascular disease in patients with gestational diabetes increased by 40%
To this end, Yu Yongfu’s team conducted a cohort study involving a large population of 1,002,486 cases, aiming to use the entire cohort and sibling pairs to analyze and explore the relationship between gestational diabetes and overall and specific cardiovascular disease risks, as well as to evaluate Whether these associations have changed due to obesity before pregnancy or a history of maternal cardiovascular disease
.
The study also used mediator analysis to quantify the impact of type 2 diabetes after gestational diabetes
The results of the study found that women with a history of gestational diabetes increased the overall risk of cardiovascular disease by 40%
.
Sibling match analysis yielded similar results (44% increase in risk)
Researchers have also observed an increased risk of specific cardiovascular diseases in gestational diabetes, including a 65% increase in the risk of stroke, and a more than two-fold increase in the risk of myocardial infarction, heart failure, and peripheral arterial disease
.
In addition, women with gestational diabetes, obesity before pregnancy, or mothers with a history of cardiovascular disease have a more pronounced increase in overall cardiovascular disease risk
Yu Yongfu said that from a public health perspective, continuous monitoring of women with a history of gestational diabetes, especially those with pre-pregnancy obesity or a history of cardiovascular disease in their mothers, is of great significance for taking effective measures to reduce cardiovascular risk
.
(Source: Sun Guogen and Huang Xin)
Related paper information: https://doi.
https://doi.
org/10.
2337/dc21-1018