The new technology of ephedrine won the first prize of Shanghai Technology Invention

The "2009 Shanghai Science and technology award conference" was held recently The "new technology of ephedrine hydrochloride production" jointly developed by Shanghai Pharmaceutical Industry Research Institute and Zhejiang PLO Kangyu Pharmaceutical Co., Ltd won the first prize of Shanghai technology invention Ephedrine products (including ephedrine, pseudoephedrine and its salts) are mainly used to stop asthma, maintain blood pressure and treat colds and colds, with a huge market demand The traditional production method uses extraction technology to extract ephedra from the sand fixing plant, which makes ephedra be exploited disorderly or even predatory, resulting in the increasingly serious desertification of the production area The "new technology of ephedrine hydrochloride production" project adopts the innovative chemical total synthesis technology, which is obviously superior to the traditional extraction technology of Ephedra at home and abroad Compared with the biological semi synthesis method and other total synthesis methods at home and abroad, it has the advantages of easy access to raw materials, convenient for large-scale production, low cost, good quality, and less three wastes At present, the two core technologies of the new process have obtained the national invention patent After technical innovation, the Comprehensive Technology Department of the project is at the leading domestic and international level, and the key technologies are also at the leading position in the world At present, the annual output of ephedrine in puluokangyu has reached 500 tons According to the calculation of the consumption of Ephedra by the traditional extraction method by relevant experts, the new process can reduce the consumption of Ephedra by 125000 tons every year and protect the 2.5 million mu grassland from damage The new technology can fundamentally solve the problem of Ephedra lack of resources, and effectively prevent grassland desertification and frequent dust storms, which has significant social and economic benefits for the protection of natural ecological environment.