 Home > Biochemistry News > Biotechnology News > The new coronavirus S protein directly binds and activates TLR4 to induce anti-bacterial innate immune response

The new coronavirus S protein directly binds and activates TLR4 to induce anti-bacterial innate immune response

 Last Update: 2021-08-11
 Source: Internet
 Author: User

Tags

blood cell morphology

human body poster

ginger immune system

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Recently, the You Fuping research group of the Institute of Systems Biomedicine of Peking University and the Wang Xiangxi research group of the Institute of Biophysics of the Chinese Academy of Sciences have published a research paper entitled "SARS-CoV-2 spike protein interacts with and activates TLR4" in Cell Research

The team purified the trimeric crown protein (1-1208aa) in vitro using 293 cells for research

The researchers also successfully inhibited the effects of the coronavirus on the above-mentioned cell experiments by using inhibitors of key molecules of the TLR4 pathway (including TLR4 inhibitor Resatovir, CD14 antibody blockade, MD2 inhibitor T5342126, and NF-κB inhibitor JSH-23).

Researcher You Fuping, Institute of Systems Biomedicine, Peking University School of Basic Medicine, and Researcher Wang Xiangxi, Institute of Biophysics, Chinese Academy of Sciences, are the co-corresponding authors

Original link: https://

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.