The new coronary pneumonia immune response male and female patients have a stronger and more sustained T-cell response.

BEIJING, Aug. 30 (Xinhua Zhang Mengran) The British journal Nature published on the 26th of an immunological study, outlining the differences in the immune response of men and women with new coronary pneumonia patients. These findings may help guide the use of a gender-based approach to the treatment of male and female patients.
studies have shown that male patients are more severe than women, but the root cause of this difference is not clear. To gain insight into the problem, a team at Yale University School of Medicine assessed 98 patients diagnosed with mild to moderate neo-coronary pneumonia at Yale-New Blackrne Hospital in the United States, aged 18 or older, with an average age of 61 to 64.
team found that female patients developed stronger and more sustained T-cell responses than male patients. T-cells are an important part of the immune system and their role includes killing infected cells. Poor T-cell response in male patients was associated with poor disease outcomes.
patients with neocyto pneumonia had higher levels of innate immunocytokines and coercides (these signaling molecules were involved in raising immune cells to inflammatory sites) compared to healthy control groups. However, some of these factors have higher levels in male patients than in female patients. In female patients, higher levels of congenitic immunocytokines were associated with poor disease response.
results suggest that male patients may benefit from therapy that improves T-cell response, while female patients may benefit from therapy that inhibits early congenitic immune responses. Still, the researchers caution that they can't rule out other potential factors that could alter the risk of poor prognosticity in both male and female patients.
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