The mystery of the longevity of amino glucose

since
1990s
amino glucose has been considered an iconic ingredient for bone and joint health. Both in the basic scientific theory of the laboratory and in clinical medical experiments, there is a large amount of data to prove that amino glucose in reducing bone joint pain and enhance bone joint function has a very good effect. Patients who have been taking amino glucose for a long time have unwittingly benefited from the fact that damage to cartilage tissue in their bone joints has slowed and surgical dependence on replacement joints has decreased, thus indirectly reducing mortality. Yes, amino glucose can make you live longer.Clinical Study of Amino GlucoseRecently, scientists used amino glucose on older mice and found that their lifespan increased, a fundamental study that became a new market growth point for amino glucose. And the basic study has two meanings:
1
) extends life by oral
means, while it's cheap and safe
; Therefore, it is not suitable for adding amino glucose to some low carbohydrates, and the effect is obvious.of course, this basic study is not based on mice alone, and it has been conducting human clinical trials since

2010 and has obtained extensive and basic experimental data from them.the study surveyed
77,700,
adults living in Washington, D.C., between the ages of
50 and 76
, U.S. scientists obtained surprising results from the study. Over the past decade, scientists have counted
20,
factors associated with mortality, including age, race, gender, smoking, exercise, and more, as well as the use of vitamins, minerals, and dietary supplements. Over the next
to
years, those who took amino glucose for at least
3
years and at least
4
times a week had a
17% reduction in
. Those who took small amounts of amino glucose (up to
3
times a week and less than
3
years) had a
8%
. However, those who already had osteoarthritis had higher mortality rates than the general population, even if they had taken large amounts of amino glucose, perhaps due to reduced exercise, more severe inflammation and lower quality sleep. So reducing the mortality rate for these patients and extending their lives will be a new revolution.In this study, the assessment of mortality reduction was not only a study of the
20,
factors, various vitamins, minerals and dietary supplements mentioned above, but also on drugs with the same anti-inflammatory effects as amino glucose and sulfur cartilage, such as aspirin, but aspirin has side effects such as haemorrhage, stroke and kidney disease.1500
milligrams is the appropriate dose?study also revealed a
effect
dose-to-dose. This means that long-term use of amino glucose is better. However, how many doses of amino glucose are required to relieve pain in the bone joints or to reduce the loss of cartilage tissue? After all, people can adjust their absorption and take oral dietary supplements or medications. We need a little background to answer this question., clinical trials of amino glucose were patented and developed as osteoarthritis drugs at a daily dose of
1500
mg. The choice of this dose was also determined after a long period of study. Today, in the development of drugs and dietary supplements, through extensive clinical trial studies, the final dose is balanced between effectiveness and safety. This does not match the dose of amino glucose.Fortunately, several clinical trial studies of amino glucose have been published in the past few years, and the results have shown that patients who take doses of more than
1,500
mg per day are better off, extending a new concept, the "knocking the door theory." If you are going to a friend's birthday party, walk to a friend's door, because the room noisy, gently knock on the door no one will hear for you to open the door, only a long time, you can finally go in, this is called the "knocking the door theory."the above analogy is similar to taking a dose of amino glucose. We know that
1500
mg of amino glucose is absorbed by both blood and bone joint membrane fluids (fluids). In a clinical absorption study, subjects took
1500
mg of amino glucose, with an average of
7.2
micromolars of amino glucose in the serum. After
3000
mg of amino glucose, the amino glucose in the subject's serum increased to an average of
13.3
micromolars. Why is this study so important? It's because high concentrations of absorption are like hitting cells with more force. Absorption levels of amino glucose inhibit specific genes in
DNA
in our bodies that cause inflammation in our bodies or cause bone cartilage tissue to break down.inhibition of these specific genes depends on the minimum concentration ingested. If the concentration is not sufficient (i.e. the intensity and loudness of the knock on the door is not enough), it will not be inhibited and will be harmful and un profiteering. The study also revealed concentrations that inhibit inflammation ranging from
7.2-13.3
micromolars. Therefore, if a person takes only
1500
mg of amino glucose per day, it will not have the effect of suppressing inflammation.differences in the absorption dosethe last challenge involved is the individual difference in the absorption dose. In the experimental study of oral amino glucose absorption, after taking
1500
mg, the maximum absorption was
5.6
times the minimum absorption. In other words, after taking
1500
mg of amino glucose at the same time, the subjects had a minimum absorption of
3.2
micromolars and a maximum absorption of
18.1
micromolars. This means that, depending on the individual,
1500
mg of amino glucose may not be able to achieve the desired absorption status.do you really need to take a dose of amino glucose? Since clinical testing methods for amino glucose intake levels have not yet been made public, they can only be judged on the basis of symptoms. After
4
months of regular intake, you should consider increasing your intake of amino glucose if your daily intake of
1500
mg does not relieve pain, improve function, or reduce the use of painkillers. I often ask my patients to increase their intake by
500
mg per month until they reach a maximum of
3000
mg of amino glucose per day.that the above dose recommendations I have made will be implemented by convenient blood tests in the future. At the same time, an increase in intake needs to be considered on the advice of a professional health consultant. In the United States, this does have the support of many doctors.