The main physiological functions of bioactive peptides

1) Enhance immunity The bioactive peptides, such as interferon and interleukin, can activate and regulate the immune response of human body and significantly improve the proliferation of human peripheral blood lymphocytes Animal realization and clinical research have proved that thymopentin plays an important role in regulating the immune function of patients with autoimmune diseases In addition, it has been shown that some small peptides produced by proteolysis have immune activity They can not only enhance the immunity of the body, but also stimulate the proliferation of lymphocytes and enhance the phagocytosis of macrophages These immunoreactive peptides can interact with intestinal mucosa associated lymphoid tissue, and can also enter the blood to interact with peripheral lymphocytes In addition, small molecular peptide can also enhance the vitality of liver cells, effectively adjust the function of lymphoid T cell subsets, enhance humoral immunity and cellular immunity, fundamentally improve human immunity, and is an effective preparation for the treatment and prevention of various liver diseases 2) Antioxidant peptides are a kind of natural active peptides which have been widely studied recently They can effectively eliminate the excess active oxygen radicals in the body, protect the normal structure of cell membrane and mitochondria, and prevent lipid peroxidation Oxidation is closely related to the natural aging of human beings and the occurrence and development of many diseases, such as cancer, diabetes, arteriosclerosis and Alzheimer's disease 3) Lowering blood pressure Antihypertensive peptide is a competitive inhibitor of angiotensin I-converting enzyme (ACE) Ace in the blood vessel can make the production of angiotension Ⅱ, which can cause the peripheral blood vessel to contract and cause the blood pressure to rise The antihypertensive peptide can inhibit the activity of ACE, prevent ace from hydrolyzing angiotension Ⅰ into angiotension Ⅱ, and reduce the production of angiotension Ⅱ At the same time, it can prevent the catalyzing hydrolysis of kallikrein, slow down the destruction of kallikrein, and then play the role of reducing the blood pressure of human body, which is prevention And effective polypeptides for the treatment of hypertension Plant derived antihypertensive peptides have been studied deeply abroad Dziuba et al Found that soybean hydrolysate has good antihypertensive effect and can inhibit ACE activity Shin et al Purified his his his Leu from soybean enzymolysis solution by HPLC, which showed that the ACE inhibitory peptide obtained from soybean protein had antihypertensive activity in animals 4) Lowering blood fat and cholesterol It has been studied and analyzed that bioactive peptides can stimulate the increase of thyroid hormone secretion, promote the bile acidification of cholesterol, increase fecal excretion of cholesterol, and thus play a role in reducing blood cholesterol Many animal experiments and clinical experiments have proved it Soybean polypeptide has the function of lowering serum cholesterol, and has special advantages compared with soybean protein For people with normal cholesterol value, there is no effect of lowering cholesterol, but for people with high cholesterol value, it has the effect of lowering cholesterol; for people with normal cholesterol value, when eating foods with high cholesterol content, it has the effect of preventing the increase of serum cholesterol value, reducing LDL value and VLDL value in cholesterol, but not HDL value 5) anticancer At present, many bioactive peptides have been found to have antitumor activity These tumor inhibitory peptides are not only the nutrients with antitumor effect, but also have been developed into antitumor drugs, and become the research hotspot of searching for anticancer drugs Natural tumor inhibitory peptides are mainly extracted from marine organisms, amphibians and many plants, some of which have been used as anticancer drugs These tumor inhibitory peptides play an anti-tumor role by directly inhibiting tumor growth, inhibiting tumor angiogenesis and activating the immune system For example, the anti-cancer peptide of scorpion venom is an effective anti-tumor peptide extracted from scorpion venom of Buthus martensii, which has obvious anti-tumor effect on many kinds of tumors, such as liver cancer and lung cancer 6) Hypoglycemia Many bioactive peptides have hypoglycemic effects Momordica charantia polypeptide is a kind of bioactive peptide, also known as plant insulin Its hypoglycemic mechanism may be to inhibit the activity of α - glucosidase in small intestinal mucosa, reduce glucose intake, protect or repair islet β cells, promote insulin secretion, especially for diabetic patients with insufficient insulin secretion In addition, bioactive polypeptides can effectively improve the body immunity, prevent the occurrence of diabetic complications, and promote the rehabilitation of diabetic patients They are ideal health food for diabetic patients 7) Eliminate fatigue Because bioactive peptides are easy to be absorbed and utilized by human body, when the body is tired due to excessive consumption of nutrients and low efficiency of various system functions, taking bioactive peptides can quickly supplement the active substances and nutrients lacking in the body, so as to improve cell metabolism, restore the maladjusted internal environment, promote the coordinated work of various systems of the body and achieve elimination The purpose of fatigue 8) Prevent thrombosis Bioactive peptides can effectively promote the production of prostacyclin in platelets, have a strong inhibitory effect on the vasoconstriction of platelet aggregation, and can resist the effect of thromboxane A 2, effectively prevent the formation of thromboxane, and play an important role in reducing the occurrence of heart and cerebrovascular diseases such as myocardial infarction and cerebral infarction More and more researchers have paid attention to the new discovery of bioactive peptides in the treatment and prevention of cardiovascular and cerebrovascular diseases.