Metabolic-related diseases, such as obesity, diabetes, high blood pressure, and high cholesterol, are among the first to be discovered as risk factors related to severe COVID-19
Recently, the research group of Professor Rongfu Wang from the University of Southern California published an important scientific paper entitled "Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication" in Nature Metabolism , confirming that the fatty acid synthesis pathway is the new coronavirus in the host cell.
Nature Metabolism The article first uses a large-scale RNA interference library (RNAi library) to screen, inhibits the expression of metabolism-related genes one by one in the host cell, and detects the infection and replication ability of the new coronavirus in it
Figure 1.
Figure 1.
Figure 2.
Figure 2.
Figure 3.
Figure 3.
Chu Junjun, a postdoctoral fellow at the University of Southern California, Changsheng Xing, an assistant professor, and Yang Du, a postdoctoral fellow, are the co-first authors of the paper
Related paper information: https://doi.
https://doi.
org/10.
1038/s42255-021-00479-4
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
