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Recently, in a research report titled "Structure of the human Mediator-bound transcription pre-initiation complex" published in the international journal Science, scientists from Northwestern University and other institutions have observed responsibility in human cells for the first time through research.
According to the researchers, the complex called Med-PIC (Mediator-bound pre-initiation complex) is the key determinant for determining which genes are activated and which genes are suppressed.
Researcher Yuan He said that in the context of gene expression, this "machine" is very basic to every branch of modern molecular biology.
The well-known biochemist Roger Kornberg discovered the mediator complex in yeast in 1990, and then won the Nolbey Prize in Chemistry in 2006.
In this study, when the researcher He and his colleagues placed the sample on a single layer of graphene oxide, they found unexpected results.
Researcher Talyzina explained that solving this complex problem is like assembling a puzzle.
Reference materials:
Reference materials:[1] R.
[1] R.
【2】Researchers reveal 3D structure responsible for gene expression
by Amanda Morris, Northwestern University
by Amanda Morris, Northwestern UniversityThis article is from Biological Valley, for more information, please download Biological Valley APP (
