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The optically captured lipid droplets in the fat cells focus the excitation light, collect the fluorescent signal from the cytoskeleton, and form an enlarged fluorescent image
With the demand for real-time monitoring of endoplasmic changes and rapid detection of extracellular signals, a large number of biological imaging methods have emerged
In a new paper published in "Optical Science and Application", Professor Li Baojun, Professor Zhang Yao and Professor Li Yuchao of the Institute of Nanophotonics of Jinan University, and Pietro from the Institute of Applied Science and Intelligent Systems (CNR-ISASI) ·The research team led by Dr.
In order to achieve intracellular imaging of subcellular structures, lipid microlenses work in a contact mode, and lipid droplets greatly improve the collection efficiency of emitted fluorescent signals
The lens effect of lipid droplets is expected to be applied to fully biocompatible miniaturized tools such as biosensing, endoscopic analysis, and single-cell diagnosis
Article title
Lipid droplets as endogenous intracellular microlenses
