The Lancet's latest report! By modifying or improving 12 risk factors, you can prevent or slow 40% of the world's dementia cases!

!--Webeditor:page title"--August 3, 2020 /PRNewswire/ -- According to the World Alzheimer's 2018 Report, one person with dementia develops every 3 seconds worldwide.
currently has at least 50 million people with dementia worldwide, and that number is expected to reach 152 million by 2050, of which about 60-70% are Alzheimer's (AD).
, there are currently about 10 million Alzheimer's patients in China, and the number of People with Alzheimer's disease in China is expected to exceed 40 million by 2050;
in recent years, as the number of young people's mortality rates has declined, including the number of older people with dementia, the incidence of age-related dementia has begun to decline in many developed countries, perhaps directly related to changes in education, nutrition, health care and lifestyle.
overall, there is growing evidence to support nine potentially modifiable risk factors simulated by the Lancet Commission for dementia prevention, intervention and care in 2017, including low levels of education, high blood pressure, hearing impairment, smoking, obesity, depression, physical inactivity, diabetes and low social exposure, a recent report published in the international journal The Lancet, "Dementia, In a review of the intervention, and care: 2020 report of the Lancet Commission, scientists from institutions such as University College London added three new and compelling risk factors, including excessive drinking, traumatic brain injury and air pollution, to the previous nine risk factors for dementia modification; And incorporating these three risk factors into the updated dementia prevention life cycle model of 12 risk factors, the researchers said it was important to prevent dementia, especially in low- or middle-income countries (LMIC), with a focus on these 12 modifiable risk factors or preventing or slowing the occurrence of 40 percent of people worldwide.
Picture Source: Gill Livingston et al. The Lancet doi: 10.1016/S0140-6736 (20) 30367-6 Researchers said that the combination of excessive drinking, traumatic brain injury and air pollution were associated with 6 percent of all dementia cases, about 3 percent of which were attributed to individuals with brain injuries occurred in middle age and 1 percent to excessive drinking in middle age (more than 21 units per week) and exposure to air pollution in later life.
the remaining nine risk factors were associated with 34 per cent of dementia, and the highest rates of dementia were low levels of early education, hearing loss in middle age, and smoking in later life (7 per cent, 8 per cent and 5 per cent, respectively).
the study, led by 28 leading global dementia researchers, based on nine risk factors associated with dementia risk factors identified by the Lancet Commission in 2017, also calls on everyone around the world to have confidence in preventing dementia, and develops a range of policy and lifestyle changes to help prevent dementia in the global population.
dementia affects the individual, family and socio-economic development, causing about $1 trillion in global damage each year. Professor Gill Livingston, the first author of the
article, said: 'This article shows that decision makers and individuals are well placed to prevent and slow the occurrence or occurrence of a large proportion of people with dementia, and also have the opportunity to have an impact at some stage in a person's life.
interventions may have the greatest impact on those who are more affected by risk factors for dementia, such as low- and middle-income countries and vulnerable groups, including blacks, Asians and ethnic minorities.
researchers point out that we need to consider not only promoting health and effectively preventing dementia, but also starting to address inequality to improve people's living conditions, and that we can also reduce the risk of dementia in people by creating positive and healthy community environments where, of course, physical activity is certainly normal, and everyone has access to a good diet and minimizes excessive drinking.
Picture Source: Gill Livingston et al. The Lancet doi: 10.1016/S0140-6736 (20) 30367-6 In order to address the risk of dementia in populations around the world, the researchers call on policymakers and individuals to take the following steps: 1) keep the body's systolic pressure below 130mmHg from about 40 years of age; Reduce hearing damage, 3) reduce exposure to air pollution and second-hand smoke, 4) prevent head injuries (especially for high-risk occupations and traffic); 5) prevent alcohol abuse and limit weekly alcohol consumption to less than 21 units, 6) stop smoking and start quitting, which is good for all age groups; 7) actively live into middle age and even late childhood; 9) reduce the incidence of obesity and diabetes.
these measures or behaviours are particularly important in low- and middle-income countries, where the incidence of dementia is higher and rising faster than in high-income countries, as a result of increased life expectancy among populations in these countries and the higher frequency of specific dementia risk factors, including low levels of education, high blood pressure, obesity, increased incidence of hearing loss and a rapid increase in the incidence of diabetes.
!--/ewebeditor:!--webeditor: "page title" - Based on a previous model that included nine risk factors, the researchers speculated that low- and middle-income countries may be able to prevent more cases of dementia than globally, with nine risk factors worldwide leading to 35 percent of dementia cases, compared with 40 percent in China, 41 percent in India and 56 percent in Latin America.
the researchers caution that because they have a conservative estimate of the prevalence of these risk factors in these populations and do not take into account the three new risk factors added in this article, the actual number of dementia patients may be higher;
researchers say the preventive assessment models used globally and in low- and middle-income countries assume a causal link between these risk factors and the onset of dementia, so they point only to some risk factors with strong evidence. Professor Adesola Ogunniyi, a
researcher, said the high prevalence of dementia risk factors in low- and middle-income countries meant that people with dementia may have a higher potential rate of prevention than high-income countries, where national policies to address dementia risk, such as universal primary and secondary education and smoking bans, may be effective and significantly prevented, and these policies will be prioritized, and researchers will need to conduct more dementia-related research in low- and middle-income countries to better understand the many dementia risk factors in these countries.
in the final part of the review, the researchers advocate holistic and individualized evidence-based care to address the physical and mental health, social care and support of people to meet the complex needs of different groups of people, while maintaining the physical health of people with dementia is important for their cognitive abilities, but often suffering from other diseases, sometimes difficult to control themselves, which can lead to potentially harmful and preventable hospitalizations over time.
researchers say people with dementia are particularly affected by COVID-19 (due to age, underlying diseases, such as high blood pressure, etc.), so physical alienation may be a challenge for people with dementia who may find it difficult to follow the guidelines or may feel very painful because they are unable to contact caregivers and family members.
While there is still a huge gap between the researchers' ultimate goals, research and awareness of risk factors for dementia, potential prevention, detection and diagnostic measures are increasing, and in this report, researchers suggest that policies and individuals who delay the incidence of cognitive impairment and dementia need to change, which may support and treat people with dementia and improve their quality of life.
, when considered as a whole, interventions to support people affected by dementia, including how to organize and coordinate complex physical diseases and social needs, can have a huge impact. The goal of
researchers is to provide enough resources for people with dementia and their caregivers globally to guide patient care and policy-making based on better evidence, and with quality care, the quality of life of people with dementia can be significantly improved and their families adequately supported.
() Source: "1" Forty per s on the dementia case be be be meme sy dyded or delayed by targeting 12 risk factors through life 2 gill Livingston, Jonathan Huntley, Andrew Sommerlad, et al. Dementia, intervention, and care: 2020 Report of the Lancet, The Lancet, July 30, 2020, doi: 10.1016/S0140-6736 (20) 30367-!-- 6