The Lancet: What are the characteristics and risks associated with deaths from breakthrough infections?

The recent recurrence of the epidemic situation can inevitably make people wonder: why the vaccine coverage rate is so high, why there are still infections ? This also led to doubts about the effectiveness of the vaccine and hesitation on whether to accept the booster shot

Recent outbreaks appear repeatedly phenomenon, can not help but wonder: vaccine coverage is so high, why there will be infected ? This also led to doubts about the effectiveness of the vaccine and hesitation on whether to accept the booster shot

Many domestic and foreign studies have provided strong evidence that vaccines can indeed effectively prevent infections, severe illnesses and deaths, especially in terms of severe illnesses and deaths, reflecting high preventive effects

However, a blockbuster news on October 19 once again caused public concern.

An article published in The Lancet on October 28 systematically studied the characteristics and related risks of deaths from new crown breakthrough infections among fully vaccinated people in Scotland

Researchers defined people who were fully vaccinated with two doses of vaccine, whether it was Pfizer, Modena or Oxford-AstraZeneca vaccine 14 days later, as fully vaccinated people, and defined individual deaths who tested positive for new crowns in fully vaccinated people as fully vaccinated people.

As of August 18, 2021, Scotland has 3,273,336 people (73.

Next, the researchers divided the fully vaccinated and unvaccinated into three groups by age: 18-64 years old, 65-79 years old, and over 80 years old, and then calculated the number of new crown-related deaths per 10,000 people in each age group.

 

In order to analyze in detail the death characteristics and related risks of the new crown of these deaths, the researchers counted whether they had any other diseases besides the new crown.

In order to analyze in detail the death characteristics and related risks of the new crown of these deaths, the researchers counted whether they had any other diseases besides the new crown.

 

Cox proportional hazards models to predict the new crown breakthrough infection risk of death, found their new crown risk of death associated with the increase in the number of comorbidities (ie, the presence of other diseases at the same time) while increasing the completely vaccinated individuals who happen crown groundbreaking new infections, there are People with five comorbidities have a significantly higher risk of new crown-related deaths than those without comorbidities.

Cox proportional hazards models to predict the new crown breakthrough infection risk of death, found their new crown risk of death associated with the increase in the number of comorbidities (ie, the presence of other diseases at the same time) while increasing the completely vaccinated individuals who happen crown groundbreaking new infections, there are People with five comorbidities have a significantly higher risk of new crown-related deaths than those without comorbidities.

In addition, according to US CDC statistics, as of October, 187 million people in the United States have received two doses of vaccine, of which more than 7,000 people have died because of breakthrough infections, with a mortality rate of about 0.

However, according to statistics from the CDC in the United States in August this year, it was found that unvaccinated patients were 11 times more likely to be infected with new crowns than fully vaccinated people, and the death rate of infections for unvaccinated people over the age of 80 was 5 times higher than that of fully vaccinated people

As many countries continue to fully open up, many people want to travel abroad or visit relatives.

References: Zoe Grange, Audrey Buelo, et al.